Properties of structural variants and short tandem repeats associated with gene expression and complex traits

Genetic variation associated with gene expression changes has mostly been studied in the context of single nucleotide variants. Here, Jakubosky et al. report eQTL analysis of structural variants and short tandem repeats and find properties, such as length of variation, that affect the association.

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Autores principales:	David Jakubosky, Matteo D’Antonio, Marc Jan Bonder, Craig Smail, Margaret K. R. Donovan, William W. Young Greenwald, Hiroko Matsui, i2QTL Consortium, Agnieszka D’Antonio-Chronowska, Oliver Stegle, Erin N. Smith, Stephen B. Montgomery, Christopher DeBoever, Kelly A. Frazer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3ac8df01ae4c4323ad093a164d82fdc4
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spelling	oai:doaj.org-article:3ac8df01ae4c4323ad093a164d82fdc42021-12-02T17:52:20ZProperties of structural variants and short tandem repeats associated with gene expression and complex traits10.1038/s41467-020-16482-42041-1723https://doaj.org/article/3ac8df01ae4c4323ad093a164d82fdc42020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16482-4https://doaj.org/toc/2041-1723Genetic variation associated with gene expression changes has mostly been studied in the context of single nucleotide variants. Here, Jakubosky et al. report eQTL analysis of structural variants and short tandem repeats and find properties, such as length of variation, that affect the association.David JakuboskyMatteo D’AntonioMarc Jan BonderCraig SmailMargaret K. R. DonovanWilliam W. Young GreenwaldHiroko Matsuii2QTL ConsortiumAgnieszka D’Antonio-ChronowskaOliver StegleErin N. SmithStephen B. MontgomeryChristopher DeBoeverKelly A. FrazerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q David Jakubosky Matteo D’Antonio Marc Jan Bonder Craig Smail Margaret K. R. Donovan William W. Young Greenwald Hiroko Matsui i2QTL Consortium Agnieszka D’Antonio-Chronowska Oliver Stegle Erin N. Smith Stephen B. Montgomery Christopher DeBoever Kelly A. Frazer Properties of structural variants and short tandem repeats associated with gene expression and complex traits
description	Genetic variation associated with gene expression changes has mostly been studied in the context of single nucleotide variants. Here, Jakubosky et al. report eQTL analysis of structural variants and short tandem repeats and find properties, such as length of variation, that affect the association.
format	article
author	David Jakubosky Matteo D’Antonio Marc Jan Bonder Craig Smail Margaret K. R. Donovan William W. Young Greenwald Hiroko Matsui i2QTL Consortium Agnieszka D’Antonio-Chronowska Oliver Stegle Erin N. Smith Stephen B. Montgomery Christopher DeBoever Kelly A. Frazer
author_facet	David Jakubosky Matteo D’Antonio Marc Jan Bonder Craig Smail Margaret K. R. Donovan William W. Young Greenwald Hiroko Matsui i2QTL Consortium Agnieszka D’Antonio-Chronowska Oliver Stegle Erin N. Smith Stephen B. Montgomery Christopher DeBoever Kelly A. Frazer
author_sort	David Jakubosky
title	Properties of structural variants and short tandem repeats associated with gene expression and complex traits
title_short	Properties of structural variants and short tandem repeats associated with gene expression and complex traits
title_full	Properties of structural variants and short tandem repeats associated with gene expression and complex traits
title_fullStr	Properties of structural variants and short tandem repeats associated with gene expression and complex traits
title_full_unstemmed	Properties of structural variants and short tandem repeats associated with gene expression and complex traits
title_sort	properties of structural variants and short tandem repeats associated with gene expression and complex traits
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/3ac8df01ae4c4323ad093a164d82fdc4
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Properties of structural variants and short tandem repeats associated with gene expression and complex traits

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