Membrane sculpting by curved DNA origami scaffolds

BAR domain proteins feature a “banana-like” shape which is thought to aid membrane scaffolding and membrane tubulation. Here authors use DNA origami mimicking BAR domains, giant unilamellar vesicles and fluorescence imaging to study how different BAR domain shapes bind and deform membranes.

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Autores principales: Henri G. Franquelim, Alena Khmelinskaia, Jean-Philippe Sobczak, Hendrik Dietz, Petra Schwille
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/3acdcdb89130437cac6c1f7874ba780f
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spelling oai:doaj.org-article:3acdcdb89130437cac6c1f7874ba780f2021-12-02T17:31:27ZMembrane sculpting by curved DNA origami scaffolds10.1038/s41467-018-03198-92041-1723https://doaj.org/article/3acdcdb89130437cac6c1f7874ba780f2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03198-9https://doaj.org/toc/2041-1723BAR domain proteins feature a “banana-like” shape which is thought to aid membrane scaffolding and membrane tubulation. Here authors use DNA origami mimicking BAR domains, giant unilamellar vesicles and fluorescence imaging to study how different BAR domain shapes bind and deform membranes.Henri G. FranquelimAlena KhmelinskaiaJean-Philippe SobczakHendrik DietzPetra SchwilleNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Henri G. Franquelim
Alena Khmelinskaia
Jean-Philippe Sobczak
Hendrik Dietz
Petra Schwille
Membrane sculpting by curved DNA origami scaffolds
description BAR domain proteins feature a “banana-like” shape which is thought to aid membrane scaffolding and membrane tubulation. Here authors use DNA origami mimicking BAR domains, giant unilamellar vesicles and fluorescence imaging to study how different BAR domain shapes bind and deform membranes.
format article
author Henri G. Franquelim
Alena Khmelinskaia
Jean-Philippe Sobczak
Hendrik Dietz
Petra Schwille
author_facet Henri G. Franquelim
Alena Khmelinskaia
Jean-Philippe Sobczak
Hendrik Dietz
Petra Schwille
author_sort Henri G. Franquelim
title Membrane sculpting by curved DNA origami scaffolds
title_short Membrane sculpting by curved DNA origami scaffolds
title_full Membrane sculpting by curved DNA origami scaffolds
title_fullStr Membrane sculpting by curved DNA origami scaffolds
title_full_unstemmed Membrane sculpting by curved DNA origami scaffolds
title_sort membrane sculpting by curved dna origami scaffolds
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/3acdcdb89130437cac6c1f7874ba780f
work_keys_str_mv AT henrigfranquelim membranesculptingbycurveddnaorigamiscaffolds
AT alenakhmelinskaia membranesculptingbycurveddnaorigamiscaffolds
AT jeanphilippesobczak membranesculptingbycurveddnaorigamiscaffolds
AT hendrikdietz membranesculptingbycurveddnaorigamiscaffolds
AT petraschwille membranesculptingbycurveddnaorigamiscaffolds
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