Membrane sculpting by curved DNA origami scaffolds
BAR domain proteins feature a “banana-like” shape which is thought to aid membrane scaffolding and membrane tubulation. Here authors use DNA origami mimicking BAR domains, giant unilamellar vesicles and fluorescence imaging to study how different BAR domain shapes bind and deform membranes.
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Nature Portfolio
2018
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oai:doaj.org-article:3acdcdb89130437cac6c1f7874ba780f2021-12-02T17:31:27ZMembrane sculpting by curved DNA origami scaffolds10.1038/s41467-018-03198-92041-1723https://doaj.org/article/3acdcdb89130437cac6c1f7874ba780f2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03198-9https://doaj.org/toc/2041-1723BAR domain proteins feature a “banana-like” shape which is thought to aid membrane scaffolding and membrane tubulation. Here authors use DNA origami mimicking BAR domains, giant unilamellar vesicles and fluorescence imaging to study how different BAR domain shapes bind and deform membranes.Henri G. FranquelimAlena KhmelinskaiaJean-Philippe SobczakHendrik DietzPetra SchwilleNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018) |
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Science Q Henri G. Franquelim Alena Khmelinskaia Jean-Philippe Sobczak Hendrik Dietz Petra Schwille Membrane sculpting by curved DNA origami scaffolds |
description |
BAR domain proteins feature a “banana-like” shape which is thought to aid membrane scaffolding and membrane tubulation. Here authors use DNA origami mimicking BAR domains, giant unilamellar vesicles and fluorescence imaging to study how different BAR domain shapes bind and deform membranes. |
format |
article |
author |
Henri G. Franquelim Alena Khmelinskaia Jean-Philippe Sobczak Hendrik Dietz Petra Schwille |
author_facet |
Henri G. Franquelim Alena Khmelinskaia Jean-Philippe Sobczak Hendrik Dietz Petra Schwille |
author_sort |
Henri G. Franquelim |
title |
Membrane sculpting by curved DNA origami scaffolds |
title_short |
Membrane sculpting by curved DNA origami scaffolds |
title_full |
Membrane sculpting by curved DNA origami scaffolds |
title_fullStr |
Membrane sculpting by curved DNA origami scaffolds |
title_full_unstemmed |
Membrane sculpting by curved DNA origami scaffolds |
title_sort |
membrane sculpting by curved dna origami scaffolds |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/3acdcdb89130437cac6c1f7874ba780f |
work_keys_str_mv |
AT henrigfranquelim membranesculptingbycurveddnaorigamiscaffolds AT alenakhmelinskaia membranesculptingbycurveddnaorigamiscaffolds AT jeanphilippesobczak membranesculptingbycurveddnaorigamiscaffolds AT hendrikdietz membranesculptingbycurveddnaorigamiscaffolds AT petraschwille membranesculptingbycurveddnaorigamiscaffolds |
_version_ |
1718380606532878336 |