Kinetics and seroprevalence of SARS-CoV-2 antibodies: a comparison of 3 different assays

Abstract Comparing seroprevalence and antibody kinetics in three different commercially available assays for SARS-CoV-2. Serostatus of COVID-19 patients was analyzed 5 months and 10 months after their infection, using three different assays: Diasorin LIAISON, Euroimmun, Abbott Diagnostics ARCHITECT....

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Autores principales:	Elisabeth Kahre, Lukas Galow, Manja Unrath, Luise Haag, Judith Blankenburg, Alexander H. Dalpke, Christian Lück, Reinhard Berner, Jakob P. Armann
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/3ad06cb755d9481f99002db848a9c614
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spelling	oai:doaj.org-article:3ad06cb755d9481f99002db848a9c6142021-12-02T16:50:25ZKinetics and seroprevalence of SARS-CoV-2 antibodies: a comparison of 3 different assays10.1038/s41598-021-94453-52045-2322https://doaj.org/article/3ad06cb755d9481f99002db848a9c6142021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-94453-5https://doaj.org/toc/2045-2322Abstract Comparing seroprevalence and antibody kinetics in three different commercially available assays for SARS-CoV-2. Serostatus of COVID-19 patients was analyzed 5 months and 10 months after their infection, using three different assays: Diasorin LIAISON, Euroimmun, Abbott Diagnostics ARCHITECT. Seropositivity at baseline differed significantly depending on the assay (Diasorin 81%, Euroimmun 83%, Abbott 59%). At follow-up antibody levels detected in the Diasorin assay were stable, while there was a significant loss in seropositivity in the Euroimmun and Abbott assays. There are significant differences in SARS-CoV-2 antibody kinetics based on the specific assay used.Elisabeth KahreLukas GalowManja UnrathLuise HaagJudith BlankenburgAlexander H. DalpkeChristian LückReinhard BernerJakob P. ArmannNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Elisabeth Kahre Lukas Galow Manja Unrath Luise Haag Judith Blankenburg Alexander H. Dalpke Christian Lück Reinhard Berner Jakob P. Armann Kinetics and seroprevalence of SARS-CoV-2 antibodies: a comparison of 3 different assays
description	Abstract Comparing seroprevalence and antibody kinetics in three different commercially available assays for SARS-CoV-2. Serostatus of COVID-19 patients was analyzed 5 months and 10 months after their infection, using three different assays: Diasorin LIAISON, Euroimmun, Abbott Diagnostics ARCHITECT. Seropositivity at baseline differed significantly depending on the assay (Diasorin 81%, Euroimmun 83%, Abbott 59%). At follow-up antibody levels detected in the Diasorin assay were stable, while there was a significant loss in seropositivity in the Euroimmun and Abbott assays. There are significant differences in SARS-CoV-2 antibody kinetics based on the specific assay used.
format	article
author	Elisabeth Kahre Lukas Galow Manja Unrath Luise Haag Judith Blankenburg Alexander H. Dalpke Christian Lück Reinhard Berner Jakob P. Armann
author_facet	Elisabeth Kahre Lukas Galow Manja Unrath Luise Haag Judith Blankenburg Alexander H. Dalpke Christian Lück Reinhard Berner Jakob P. Armann
author_sort	Elisabeth Kahre
title	Kinetics and seroprevalence of SARS-CoV-2 antibodies: a comparison of 3 different assays
title_short	Kinetics and seroprevalence of SARS-CoV-2 antibodies: a comparison of 3 different assays
title_full	Kinetics and seroprevalence of SARS-CoV-2 antibodies: a comparison of 3 different assays
title_fullStr	Kinetics and seroprevalence of SARS-CoV-2 antibodies: a comparison of 3 different assays
title_full_unstemmed	Kinetics and seroprevalence of SARS-CoV-2 antibodies: a comparison of 3 different assays
title_sort	kinetics and seroprevalence of sars-cov-2 antibodies: a comparison of 3 different assays
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/3ad06cb755d9481f99002db848a9c614
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Kinetics and seroprevalence of SARS-CoV-2 antibodies: a comparison of 3 different assays

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