Comparison of the antiremodeling effects of losartan and mirabegron in a rat model of uremic cardiomyopathy

Comparison of the antiremodeling effects of losartan and mirabegron in a rat model of uremic cardiomyopathy

Abstract Uremic cardiomyopathy is characterized by diastolic dysfunction (DD), left ventricular hypertrophy (LVH), and fibrosis. Angiotensin-II plays a major role in the development of uremic cardiomyopathy via nitro-oxidative and inflammatory mechanisms. In heart failure, the beta-3 adrenergic rece...

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Main Authors: Zsuzsanna Z. A. Kovács, Gergő Szűcs, Marah Freiwan, Mónika G. Kovács, Fanni M. Márványkövi, Hoa Dinh, Andrea Siska, Katalin Farkas, Ferenc Kovács, András Kriston, Péter Horváth, Bence Kővári, Bálint Gábor Cserni, Gábor Cserni, Imre Földesi, Tamás Csont, Márta Sárközy
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/3ad90176f4df4c6c9713c509cda2b33c
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https://doaj.org/article/3ad90176f4df4c6c9713c509cda2b33c

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