Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms

Pathogenic bacteria can aggregate to form biofilms and develop tolerance to antibiotics. Here, the authors use a proteomics approach to study the development of tolerance to the antibiotic colistin in Pseudomonas aeruginosabiofilms, and show that co-treatment with a second compound kills the toleran...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Song Lin Chua, Joey Kuok Hoong Yam, Piliang Hao, Sunil S. Adav, May Margarette Salido, Yang Liu, Michael Givskov, Siu Kwan Sze, Tim Tolker-Nielsen, Liang Yang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3ada21e3a86f427faa6e6a5a15d8d8e5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:3ada21e3a86f427faa6e6a5a15d8d8e5
record_format	dspace
spelling	oai:doaj.org-article:3ada21e3a86f427faa6e6a5a15d8d8e52021-12-02T15:33:50ZSelective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms10.1038/ncomms107502041-1723https://doaj.org/article/3ada21e3a86f427faa6e6a5a15d8d8e52016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10750https://doaj.org/toc/2041-1723Pathogenic bacteria can aggregate to form biofilms and develop tolerance to antibiotics. Here, the authors use a proteomics approach to study the development of tolerance to the antibiotic colistin in Pseudomonas aeruginosabiofilms, and show that co-treatment with a second compound kills the tolerant cells.Song Lin ChuaJoey Kuok Hoong YamPiliang HaoSunil S. AdavMay Margarette SalidoYang LiuMichael GivskovSiu Kwan SzeTim Tolker-NielsenLiang YangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Song Lin Chua Joey Kuok Hoong Yam Piliang Hao Sunil S. Adav May Margarette Salido Yang Liu Michael Givskov Siu Kwan Sze Tim Tolker-Nielsen Liang Yang Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms
description	Pathogenic bacteria can aggregate to form biofilms and develop tolerance to antibiotics. Here, the authors use a proteomics approach to study the development of tolerance to the antibiotic colistin in Pseudomonas aeruginosabiofilms, and show that co-treatment with a second compound kills the tolerant cells.
format	article
author	Song Lin Chua Joey Kuok Hoong Yam Piliang Hao Sunil S. Adav May Margarette Salido Yang Liu Michael Givskov Siu Kwan Sze Tim Tolker-Nielsen Liang Yang
author_facet	Song Lin Chua Joey Kuok Hoong Yam Piliang Hao Sunil S. Adav May Margarette Salido Yang Liu Michael Givskov Siu Kwan Sze Tim Tolker-Nielsen Liang Yang
author_sort	Song Lin Chua
title	Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms
title_short	Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms
title_full	Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms
title_fullStr	Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms
title_full_unstemmed	Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms
title_sort	selective labelling and eradication of antibiotic-tolerant bacterial populations in pseudomonas aeruginosa biofilms
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/3ada21e3a86f427faa6e6a5a15d8d8e5
work_keys_str_mv	AT songlinchua selectivelabellinganderadicationofantibiotictolerantbacterialpopulationsinpseudomonasaeruginosabiofilms AT joeykuokhoongyam selectivelabellinganderadicationofantibiotictolerantbacterialpopulationsinpseudomonasaeruginosabiofilms AT pilianghao selectivelabellinganderadicationofantibiotictolerantbacterialpopulationsinpseudomonasaeruginosabiofilms AT sunilsadav selectivelabellinganderadicationofantibiotictolerantbacterialpopulationsinpseudomonasaeruginosabiofilms AT maymargarettesalido selectivelabellinganderadicationofantibiotictolerantbacterialpopulationsinpseudomonasaeruginosabiofilms AT yangliu selectivelabellinganderadicationofantibiotictolerantbacterialpopulationsinpseudomonasaeruginosabiofilms AT michaelgivskov selectivelabellinganderadicationofantibiotictolerantbacterialpopulationsinpseudomonasaeruginosabiofilms AT siukwansze selectivelabellinganderadicationofantibiotictolerantbacterialpopulationsinpseudomonasaeruginosabiofilms AT timtolkernielsen selectivelabellinganderadicationofantibiotictolerantbacterialpopulationsinpseudomonasaeruginosabiofilms AT liangyang selectivelabellinganderadicationofantibiotictolerantbacterialpopulationsinpseudomonasaeruginosabiofilms
_version_	1718387017731014656

Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms

Ejemplares similares