Nanolayered composite with enhanced ultraviolet ray absorption properties from simultaneous intercalation of sunscreen molecules

Sumaiyah Megat Nabil Mohsin,1 Mohd Zobir Hussein,2 Siti Halimah Sarijo,3 Sharida Fakurazi,4,5 Palanisamy Arulselvan,6,7 Yun Hin Taufiq-Yap8 1Advanced Oleochemical Technology Division (AOTD), Malaysian Palm Oil Board (MPOB), Kajang, Selangor, Malaysia; 2Material Synthesis and Characterization Labora...

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Autores principales:	Megat Nabil Mohsin S, Hussein MZ, Sarijo SH, Fakurazi S, Arulselvan P, Taufiq-Yap YH
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Biocompatibility cell viability dermis layered double hydroxide nanocomposite Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/3ae53f090ca54df4938775152134e159
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spelling	oai:doaj.org-article:3ae53f090ca54df4938775152134e1592021-12-02T07:04:49ZNanolayered composite with enhanced ultraviolet ray absorption properties from simultaneous intercalation of sunscreen molecules1178-2013https://doaj.org/article/3ae53f090ca54df4938775152134e1592018-10-01T00:00:00Zhttps://www.dovepress.com/nanolayered-composite-with-enhanced-ultraviolet-ray-absorption-propert-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Sumaiyah Megat Nabil Mohsin,1 Mohd Zobir Hussein,2 Siti Halimah Sarijo,3 Sharida Fakurazi,4,5 Palanisamy Arulselvan,6,7 Yun Hin Taufiq-Yap8 1Advanced Oleochemical Technology Division (AOTD), Malaysian Palm Oil Board (MPOB), Kajang, Selangor, Malaysia; 2Material Synthesis and Characterization Laboratory (MSCL), Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, Serdang, Selangor, Malaysia; 3Faculty of Applied Science, Universiti Teknologi MARA, Shah Alam, Selangor, Malaysia; 4Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia; 5Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor, Malaysia; 6Muthayammal Centre for Advanced Research, Muthayammal College of Arts and Science, Rasipuram, Namakkal, Tamil Nadu, India; 7Scigen Research and Innovation, Periyar Technology Business Incubator, Thanjavur, Tamil Nadu, India; 8Catalysis Science and Technology Research Centre, Faculty of Science, Universiti Putra Malaysia, Serdang, Selangor, Malaysia Introduction: The potential of layered double hydroxide (LDH) as a host of multiple ultraviolet-ray absorbers was investigated by simultaneous intercalation of benzophenone 4 (B4) and Eusolex® 232 (EUS) in Zn/Al LDH.Methods: The nanocomposites were prepared via coprecipitation method at various molar ratios of B4 and EUS.Results: At equal molar ratios, the obtained nanocomposite showed an intercalation selectivity that is preferential to EUS. However, the selectivity ratio of intercalated anions was shown to be capable of being altered by adjusting the molar ratio of intended guests during synthesis. Dual-guest nanocomposite synthesized with B4:EUS molar ratio 3:1 (ZEB [3:1]) showed an intercalation selectivity ratio of B4:EUS =53:47. Properties of ZEB (3:1) were monitored using powder X-ray diffractometer to show a basal spacing of 21.8 Å. Direct-injection mass spectra, Fourier transform infrared spectra, and ultraviolet–visible spectra confirmed the dual intercalation of both anions into the interlayer regions of dual-guest nanocomposite. The cytotoxicity study of dual-guest nanocomposite ZEB (3:1) on human dermal fibroblast cells showed no significant toxicity until 25 µg/mL. Conclusion: Overall, the findings demonstrate successful customization of ultraviolet-ray absorbers composition in LDH host. Keywords: biocompatibility, cell viability, dermis, layered double hydroxide, nanocompositeMegat Nabil Mohsin SHussein MZSarijo SHFakurazi SArulselvan PTaufiq-Yap YHDove Medical PressarticleBiocompatibilitycell viabilitydermislayered double hydroxidenanocompositeMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 13, Pp 6359-6374 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biocompatibility cell viability dermis layered double hydroxide nanocomposite Medicine (General) R5-920
spellingShingle	Biocompatibility cell viability dermis layered double hydroxide nanocomposite Medicine (General) R5-920 Megat Nabil Mohsin S Hussein MZ Sarijo SH Fakurazi S Arulselvan P Taufiq-Yap YH Nanolayered composite with enhanced ultraviolet ray absorption properties from simultaneous intercalation of sunscreen molecules
description	Sumaiyah Megat Nabil Mohsin,1 Mohd Zobir Hussein,2 Siti Halimah Sarijo,3 Sharida Fakurazi,4,5 Palanisamy Arulselvan,6,7 Yun Hin Taufiq-Yap8 1Advanced Oleochemical Technology Division (AOTD), Malaysian Palm Oil Board (MPOB), Kajang, Selangor, Malaysia; 2Material Synthesis and Characterization Laboratory (MSCL), Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, Serdang, Selangor, Malaysia; 3Faculty of Applied Science, Universiti Teknologi MARA, Shah Alam, Selangor, Malaysia; 4Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia; 5Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor, Malaysia; 6Muthayammal Centre for Advanced Research, Muthayammal College of Arts and Science, Rasipuram, Namakkal, Tamil Nadu, India; 7Scigen Research and Innovation, Periyar Technology Business Incubator, Thanjavur, Tamil Nadu, India; 8Catalysis Science and Technology Research Centre, Faculty of Science, Universiti Putra Malaysia, Serdang, Selangor, Malaysia Introduction: The potential of layered double hydroxide (LDH) as a host of multiple ultraviolet-ray absorbers was investigated by simultaneous intercalation of benzophenone 4 (B4) and Eusolex® 232 (EUS) in Zn/Al LDH.Methods: The nanocomposites were prepared via coprecipitation method at various molar ratios of B4 and EUS.Results: At equal molar ratios, the obtained nanocomposite showed an intercalation selectivity that is preferential to EUS. However, the selectivity ratio of intercalated anions was shown to be capable of being altered by adjusting the molar ratio of intended guests during synthesis. Dual-guest nanocomposite synthesized with B4:EUS molar ratio 3:1 (ZEB [3:1]) showed an intercalation selectivity ratio of B4:EUS =53:47. Properties of ZEB (3:1) were monitored using powder X-ray diffractometer to show a basal spacing of 21.8 Å. Direct-injection mass spectra, Fourier transform infrared spectra, and ultraviolet–visible spectra confirmed the dual intercalation of both anions into the interlayer regions of dual-guest nanocomposite. The cytotoxicity study of dual-guest nanocomposite ZEB (3:1) on human dermal fibroblast cells showed no significant toxicity until 25 µg/mL. Conclusion: Overall, the findings demonstrate successful customization of ultraviolet-ray absorbers composition in LDH host. Keywords: biocompatibility, cell viability, dermis, layered double hydroxide, nanocomposite
format	article
author	Megat Nabil Mohsin S Hussein MZ Sarijo SH Fakurazi S Arulselvan P Taufiq-Yap YH
author_facet	Megat Nabil Mohsin S Hussein MZ Sarijo SH Fakurazi S Arulselvan P Taufiq-Yap YH
author_sort	Megat Nabil Mohsin S
title	Nanolayered composite with enhanced ultraviolet ray absorption properties from simultaneous intercalation of sunscreen molecules
title_short	Nanolayered composite with enhanced ultraviolet ray absorption properties from simultaneous intercalation of sunscreen molecules
title_full	Nanolayered composite with enhanced ultraviolet ray absorption properties from simultaneous intercalation of sunscreen molecules
title_fullStr	Nanolayered composite with enhanced ultraviolet ray absorption properties from simultaneous intercalation of sunscreen molecules
title_full_unstemmed	Nanolayered composite with enhanced ultraviolet ray absorption properties from simultaneous intercalation of sunscreen molecules
title_sort	nanolayered composite with enhanced ultraviolet ray absorption properties from simultaneous intercalation of sunscreen molecules
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/3ae53f090ca54df4938775152134e159
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_version_	1718399626168500224

Nanolayered composite with enhanced ultraviolet ray absorption properties from simultaneous intercalation of sunscreen molecules

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