A SUMO-dependent feedback loop senses and controls the biogenesis of nuclear pore subunits

A SUMO-dependent feedback loop senses and controls the biogenesis of nuclear pore subunits

The nuclear pore complex is crucial for mediating nucleocytoplasmic exchanges. Here the authors use budding yeast to reveal a mechanism responsible of maintaining nucleoporin homeostasis by sensing changes in the complex integrity and further altering the metabolism of the corresponding mRNAs.

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Autores principales: Jérôme O. Rouvière, Manuel Bulfoni, Alex Tuck, Bertrand Cosson, Frédéric Devaux, Benoit Palancade
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/3ae6f3fa0ffa410b9db7fd97b66e5a78
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