Sulforaphane Targets TRA-1/GLI Upstream of DAF-16/FOXO to Promote C. elegans Longevity and Healthspan
Broccoli-derived isothiocyanate sulforaphane inhibits inflammation and cancer. Sulforaphane may support healthy aging, but the underlying detailed mechanisms are unclear. We used the C. elegans nematode model to address this question. Wild-type and 4 mutant C. elegans worm strains were fed in the pr...
Guardado en:
Autores principales: | Huihui Ji, Zhimin Qi, Daniel Schrapel, Monika Le, Yiqiao Luo, Bin Yan, Jury Gladkich, Michael Schaefer, Li Liu, Ingrid Herr |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/3afcecfa695644f9942df44b98c6a16c |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Transcriptome Analysis of Insulin Signaling-Associated Transcription Factors in <i>C. elegans</i> Reveal Their Genome-Wide Target Genes Specificity and Complexity
por: Neha Kaushik, et al.
Publicado: (2021) -
Studies on statistical optimization of sulforaphane production from broccoli seed
por: Wu,Yuanfeng, et al.
Publicado: (2013) -
Ethanol Alleviates Amyloid-β-Induced Toxicity in an Alzheimer’s Disease Model of Caenorhabiditis elegans
por: Shuju Bai, et al.
Publicado: (2021) -
A Physiological-Based Model for Simulating the Bioavailability and Kinetics of Sulforaphane from Broccoli Products
por: Quchat Shekarri, et al.
Publicado: (2021) -
Protective effects of broccoli extracts and sulforaphane against hydrogen peroxide induced oxidative stress in B16 cells
por: Yao Zhang, et al.
Publicado: (2021)