Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy

Enzymatic reactions caused by neutrophils can cause the elevation of reactive oxygen species (ROS) in tumour tissue, Here, the authors, inspired by the neutrophils, design and test a synthetic cascade reaction which turns ROS into singlet oxygen and demonstrate the application of the designed nanopa...

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Autores principales:	Qing Wu, Zhigang He, Xia Wang, Qi Zhang, Qingcong Wei, Sunqiang Ma, Cheng Ma, Jiyu Li, Qigang Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3b01bc0ceb0948a497595aa20af974c0
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spelling	oai:doaj.org-article:3b01bc0ceb0948a497595aa20af974c02021-12-02T15:35:47ZCascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy10.1038/s41467-018-08234-22041-1723https://doaj.org/article/3b01bc0ceb0948a497595aa20af974c02019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08234-2https://doaj.org/toc/2041-1723Enzymatic reactions caused by neutrophils can cause the elevation of reactive oxygen species (ROS) in tumour tissue, Here, the authors, inspired by the neutrophils, design and test a synthetic cascade reaction which turns ROS into singlet oxygen and demonstrate the application of the designed nanoparticleQing WuZhigang HeXia WangQi ZhangQingcong WeiSunqiang MaCheng MaJiyu LiQigang WangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qing Wu Zhigang He Xia Wang Qi Zhang Qingcong Wei Sunqiang Ma Cheng Ma Jiyu Li Qigang Wang Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy
description	Enzymatic reactions caused by neutrophils can cause the elevation of reactive oxygen species (ROS) in tumour tissue, Here, the authors, inspired by the neutrophils, design and test a synthetic cascade reaction which turns ROS into singlet oxygen and demonstrate the application of the designed nanoparticle
format	article
author	Qing Wu Zhigang He Xia Wang Qi Zhang Qingcong Wei Sunqiang Ma Cheng Ma Jiyu Li Qigang Wang
author_facet	Qing Wu Zhigang He Xia Wang Qi Zhang Qingcong Wei Sunqiang Ma Cheng Ma Jiyu Li Qigang Wang
author_sort	Qing Wu
title	Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy
title_short	Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy
title_full	Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy
title_fullStr	Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy
title_full_unstemmed	Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy
title_sort	cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/3b01bc0ceb0948a497595aa20af974c0
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Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy

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