Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy

Enzymatic reactions caused by neutrophils can cause the elevation of reactive oxygen species (ROS) in tumour tissue, Here, the authors, inspired by the neutrophils, design and test a synthetic cascade reaction which turns ROS into singlet oxygen and demonstrate the application of the designed nanopa...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Qing Wu, Zhigang He, Xia Wang, Qi Zhang, Qingcong Wei, Sunqiang Ma, Cheng Ma, Jiyu Li, Qigang Wang
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2019
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/3b01bc0ceb0948a497595aa20af974c0
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

id	oai:doaj.org-article:3b01bc0ceb0948a497595aa20af974c0
record_format	dspace
spelling	oai:doaj.org-article:3b01bc0ceb0948a497595aa20af974c02021-12-02T15:35:47ZCascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy10.1038/s41467-018-08234-22041-1723https://doaj.org/article/3b01bc0ceb0948a497595aa20af974c02019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08234-2https://doaj.org/toc/2041-1723Enzymatic reactions caused by neutrophils can cause the elevation of reactive oxygen species (ROS) in tumour tissue, Here, the authors, inspired by the neutrophils, design and test a synthetic cascade reaction which turns ROS into singlet oxygen and demonstrate the application of the designed nanoparticleQing WuZhigang HeXia WangQi ZhangQingcong WeiSunqiang MaCheng MaJiyu LiQigang WangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qing Wu Zhigang He Xia Wang Qi Zhang Qingcong Wei Sunqiang Ma Cheng Ma Jiyu Li Qigang Wang Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy
description	Enzymatic reactions caused by neutrophils can cause the elevation of reactive oxygen species (ROS) in tumour tissue, Here, the authors, inspired by the neutrophils, design and test a synthetic cascade reaction which turns ROS into singlet oxygen and demonstrate the application of the designed nanoparticle
format	article
author	Qing Wu Zhigang He Xia Wang Qi Zhang Qingcong Wei Sunqiang Ma Cheng Ma Jiyu Li Qigang Wang
author_facet	Qing Wu Zhigang He Xia Wang Qi Zhang Qingcong Wei Sunqiang Ma Cheng Ma Jiyu Li Qigang Wang
author_sort	Qing Wu
title	Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy
title_short	Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy
title_full	Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy
title_fullStr	Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy
title_full_unstemmed	Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy
title_sort	cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/3b01bc0ceb0948a497595aa20af974c0
work_keys_str_mv	AT qingwu cascadeenzymeswithinselfassembledhybridnanogelmimickedneutrophillysosomesforsingletoxygenelevatedcancertherapy AT zhiganghe cascadeenzymeswithinselfassembledhybridnanogelmimickedneutrophillysosomesforsingletoxygenelevatedcancertherapy AT xiawang cascadeenzymeswithinselfassembledhybridnanogelmimickedneutrophillysosomesforsingletoxygenelevatedcancertherapy AT qizhang cascadeenzymeswithinselfassembledhybridnanogelmimickedneutrophillysosomesforsingletoxygenelevatedcancertherapy AT qingcongwei cascadeenzymeswithinselfassembledhybridnanogelmimickedneutrophillysosomesforsingletoxygenelevatedcancertherapy AT sunqiangma cascadeenzymeswithinselfassembledhybridnanogelmimickedneutrophillysosomesforsingletoxygenelevatedcancertherapy AT chengma cascadeenzymeswithinselfassembledhybridnanogelmimickedneutrophillysosomesforsingletoxygenelevatedcancertherapy AT jiyuli cascadeenzymeswithinselfassembledhybridnanogelmimickedneutrophillysosomesforsingletoxygenelevatedcancertherapy AT qigangwang cascadeenzymeswithinselfassembledhybridnanogelmimickedneutrophillysosomesforsingletoxygenelevatedcancertherapy
_version_	1718386466530263040

Cascade enzymes within self-assembled hybrid nanogel mimicked neutrophil lysosomes for singlet oxygen elevated cancer therapy

Documents similaires