Primary effusion lymphoma enhancer connectome links super-enhancers to dependency factors

Primary effusion lymphoma enhancer connectome links super-enhancers to dependency factors

Primary effusion lymphoma (PEL) has a very poor prognosis. Here, the authors perform H3K27ac HiChIP in PEL cells and generate the PEL enhancer connectome, linking enhancers and promoters in PEL, as well as super-enhancers to dependency factors.

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Detalles Bibliográficos
Autores principales: Chong Wang, Luyao Zhang, Liangru Ke, Weiyue Ding, Sizun Jiang, Difei Li, Yohei Narita, Isabella Hou, Jun Liang, Shijun Li, Haipeng Xiao, Eva Gottwein, Kenneth M. Kaye, Mingxiang Teng, Bo Zhao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
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Acceso en línea:https://doaj.org/article/3b0cb7b6da294c72b4d1187e13551c79
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