Sequence validation of candidates for selectively important genes in sunflower.

Analyses aimed at identifying genes that have been targeted by past selection provide a powerful means for investigating the molecular basis of adaptive differentiation. In the case of crop plants, such studies have the potential to not only shed light on important evolutionary processes, but also t...

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Autores principales:	Mark A Chapman, Jennifer R Mandel, John M Burke
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/3b10a50b266e4b708fafb94bd6752d72
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spelling	oai:doaj.org-article:3b10a50b266e4b708fafb94bd6752d722021-11-18T08:58:16ZSequence validation of candidates for selectively important genes in sunflower.1932-620310.1371/journal.pone.0071941https://doaj.org/article/3b10a50b266e4b708fafb94bd6752d722013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23991009/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Analyses aimed at identifying genes that have been targeted by past selection provide a powerful means for investigating the molecular basis of adaptive differentiation. In the case of crop plants, such studies have the potential to not only shed light on important evolutionary processes, but also to identify genes of agronomic interest. In this study, we test for evidence of positive selection at the DNA sequence level in a set of candidate genes previously identified in a genome-wide scan for genotypic evidence of selection during the evolution of cultivated sunflower. In the majority of cases, we were able to confirm the effects of selection in shaping diversity at these loci. Notably, the genes that were found to be under selection via our sequence-based analyses were devoid of variation in the cultivated sunflower gene pool. This result confirms a possible strategy for streamlining the search for adaptively-important loci process by pre-screening the derived population to identify the strongest candidates before sequencing them in the ancestral population.Mark A ChapmanJennifer R MandelJohn M BurkePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 8, p e71941 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mark A Chapman Jennifer R Mandel John M Burke Sequence validation of candidates for selectively important genes in sunflower.
description	Analyses aimed at identifying genes that have been targeted by past selection provide a powerful means for investigating the molecular basis of adaptive differentiation. In the case of crop plants, such studies have the potential to not only shed light on important evolutionary processes, but also to identify genes of agronomic interest. In this study, we test for evidence of positive selection at the DNA sequence level in a set of candidate genes previously identified in a genome-wide scan for genotypic evidence of selection during the evolution of cultivated sunflower. In the majority of cases, we were able to confirm the effects of selection in shaping diversity at these loci. Notably, the genes that were found to be under selection via our sequence-based analyses were devoid of variation in the cultivated sunflower gene pool. This result confirms a possible strategy for streamlining the search for adaptively-important loci process by pre-screening the derived population to identify the strongest candidates before sequencing them in the ancestral population.
format	article
author	Mark A Chapman Jennifer R Mandel John M Burke
author_facet	Mark A Chapman Jennifer R Mandel John M Burke
author_sort	Mark A Chapman
title	Sequence validation of candidates for selectively important genes in sunflower.
title_short	Sequence validation of candidates for selectively important genes in sunflower.
title_full	Sequence validation of candidates for selectively important genes in sunflower.
title_fullStr	Sequence validation of candidates for selectively important genes in sunflower.
title_full_unstemmed	Sequence validation of candidates for selectively important genes in sunflower.
title_sort	sequence validation of candidates for selectively important genes in sunflower.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/3b10a50b266e4b708fafb94bd6752d72
work_keys_str_mv	AT markachapman sequencevalidationofcandidatesforselectivelyimportantgenesinsunflower AT jenniferrmandel sequencevalidationofcandidatesforselectivelyimportantgenesinsunflower AT johnmburke sequencevalidationofcandidatesforselectivelyimportantgenesinsunflower
_version_	1718421075323256832

Sequence validation of candidates for selectively important genes in sunflower.

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