Cell Therapy for Neurological Disorders: The Perspective of Promising Cells
Neurological disorders are big public health challenges that are afflicting hundreds of millions of people around the world. Although many conventional pharmacological therapies have been tested in patients, their therapeutic efficacies to alleviate their symptoms and slow down the course of the dis...
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MDPI AG
2021
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oai:doaj.org-article:3b1c23fbf5ee4642a15a1719ccc9b2d52021-11-25T16:47:25ZCell Therapy for Neurological Disorders: The Perspective of Promising Cells10.3390/biology101111422079-7737https://doaj.org/article/3b1c23fbf5ee4642a15a1719ccc9b2d52021-11-01T00:00:00Zhttps://www.mdpi.com/2079-7737/10/11/1142https://doaj.org/toc/2079-7737Neurological disorders are big public health challenges that are afflicting hundreds of millions of people around the world. Although many conventional pharmacological therapies have been tested in patients, their therapeutic efficacies to alleviate their symptoms and slow down the course of the diseases are usually limited. Cell therapy has attracted the interest of many researchers in the last several decades and has brought new hope for treating neurological disorders. Moreover, numerous studies have shown promising results. However, none of the studies has led to a promising therapy for patients with neurological disorders, despite the ongoing and completed clinical trials. There are many factors that may affect the outcome of cell therapy for neurological disorders due to the complexity of the nervous system, especially cell types for transplantation and the specific disease for treatment. This paper provides a review of the various cell types from humans that may be clinically used for neurological disorders, based on their characteristics and current progress in related studies.Donghui LiuLarisa BobrovskayaXin-Fu ZhouMDPI AGarticlecell therapycell transplantationneurological disordersstem cellsclinical trialsBiology (General)QH301-705.5ENBiology, Vol 10, Iss 1142, p 1142 (2021) |
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cell therapy cell transplantation neurological disorders stem cells clinical trials Biology (General) QH301-705.5 |
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cell therapy cell transplantation neurological disorders stem cells clinical trials Biology (General) QH301-705.5 Donghui Liu Larisa Bobrovskaya Xin-Fu Zhou Cell Therapy for Neurological Disorders: The Perspective of Promising Cells |
description |
Neurological disorders are big public health challenges that are afflicting hundreds of millions of people around the world. Although many conventional pharmacological therapies have been tested in patients, their therapeutic efficacies to alleviate their symptoms and slow down the course of the diseases are usually limited. Cell therapy has attracted the interest of many researchers in the last several decades and has brought new hope for treating neurological disorders. Moreover, numerous studies have shown promising results. However, none of the studies has led to a promising therapy for patients with neurological disorders, despite the ongoing and completed clinical trials. There are many factors that may affect the outcome of cell therapy for neurological disorders due to the complexity of the nervous system, especially cell types for transplantation and the specific disease for treatment. This paper provides a review of the various cell types from humans that may be clinically used for neurological disorders, based on their characteristics and current progress in related studies. |
format |
article |
author |
Donghui Liu Larisa Bobrovskaya Xin-Fu Zhou |
author_facet |
Donghui Liu Larisa Bobrovskaya Xin-Fu Zhou |
author_sort |
Donghui Liu |
title |
Cell Therapy for Neurological Disorders: The Perspective of Promising Cells |
title_short |
Cell Therapy for Neurological Disorders: The Perspective of Promising Cells |
title_full |
Cell Therapy for Neurological Disorders: The Perspective of Promising Cells |
title_fullStr |
Cell Therapy for Neurological Disorders: The Perspective of Promising Cells |
title_full_unstemmed |
Cell Therapy for Neurological Disorders: The Perspective of Promising Cells |
title_sort |
cell therapy for neurological disorders: the perspective of promising cells |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/3b1c23fbf5ee4642a15a1719ccc9b2d5 |
work_keys_str_mv |
AT donghuiliu celltherapyforneurologicaldisorderstheperspectiveofpromisingcells AT larisabobrovskaya celltherapyforneurologicaldisorderstheperspectiveofpromisingcells AT xinfuzhou celltherapyforneurologicaldisorderstheperspectiveofpromisingcells |
_version_ |
1718412948074921984 |