14-3-3 proteins regulate Tctp–Rheb interaction for organ growth in Drosophila
14-3-3 proteins regulate several signalling pathways but often act redundantly; however, the molecular mechanisms behind such redundancy are unclear. Here, the authors show that 14-3-3 proteins regulate two interacting components of Tor signalling in Drosophila, Tctp and Rheb, disrupting organ devel...
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Auteurs principaux: | , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2016
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Accès en ligne: | https://doaj.org/article/3b1e8c0b1da148e8a191c239633cbfee |
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Résumé: | 14-3-3 proteins regulate several signalling pathways but often act redundantly; however, the molecular mechanisms behind such redundancy are unclear. Here, the authors show that 14-3-3 proteins regulate two interacting components of Tor signalling in Drosophila, Tctp and Rheb, disrupting organ development. |
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