14-3-3 proteins regulate Tctp–Rheb interaction for organ growth in Drosophila

14-3-3 proteins regulate several signalling pathways but often act redundantly; however, the molecular mechanisms behind such redundancy are unclear. Here, the authors show that 14-3-3 proteins regulate two interacting components of Tor signalling in Drosophila, Tctp and Rheb, disrupting organ devel...

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Autores principales: Thao Phuong Le, Linh Thuong Vuong, Ah-Ram Kim, Ya-Chieh Hsu, Kwang-Wook Choi
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/3b1e8c0b1da148e8a191c239633cbfee
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spelling oai:doaj.org-article:3b1e8c0b1da148e8a191c239633cbfee2021-12-02T15:35:19Z14-3-3 proteins regulate Tctp–Rheb interaction for organ growth in Drosophila10.1038/ncomms115012041-1723https://doaj.org/article/3b1e8c0b1da148e8a191c239633cbfee2016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11501https://doaj.org/toc/2041-172314-3-3 proteins regulate several signalling pathways but often act redundantly; however, the molecular mechanisms behind such redundancy are unclear. Here, the authors show that 14-3-3 proteins regulate two interacting components of Tor signalling in Drosophila, Tctp and Rheb, disrupting organ development.Thao Phuong LeLinh Thuong VuongAh-Ram KimYa-Chieh HsuKwang-Wook ChoiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Thao Phuong Le
Linh Thuong Vuong
Ah-Ram Kim
Ya-Chieh Hsu
Kwang-Wook Choi
14-3-3 proteins regulate Tctp–Rheb interaction for organ growth in Drosophila
description 14-3-3 proteins regulate several signalling pathways but often act redundantly; however, the molecular mechanisms behind such redundancy are unclear. Here, the authors show that 14-3-3 proteins regulate two interacting components of Tor signalling in Drosophila, Tctp and Rheb, disrupting organ development.
format article
author Thao Phuong Le
Linh Thuong Vuong
Ah-Ram Kim
Ya-Chieh Hsu
Kwang-Wook Choi
author_facet Thao Phuong Le
Linh Thuong Vuong
Ah-Ram Kim
Ya-Chieh Hsu
Kwang-Wook Choi
author_sort Thao Phuong Le
title 14-3-3 proteins regulate Tctp–Rheb interaction for organ growth in Drosophila
title_short 14-3-3 proteins regulate Tctp–Rheb interaction for organ growth in Drosophila
title_full 14-3-3 proteins regulate Tctp–Rheb interaction for organ growth in Drosophila
title_fullStr 14-3-3 proteins regulate Tctp–Rheb interaction for organ growth in Drosophila
title_full_unstemmed 14-3-3 proteins regulate Tctp–Rheb interaction for organ growth in Drosophila
title_sort 14-3-3 proteins regulate tctp–rheb interaction for organ growth in drosophila
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/3b1e8c0b1da148e8a191c239633cbfee
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AT yachiehhsu 1433proteinsregulatetctprhebinteractionfororgangrowthindrosophila
AT kwangwookchoi 1433proteinsregulatetctprhebinteractionfororgangrowthindrosophila
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