FEATURES NEUTROPHIL CHEMILUMINESCENCE OF PERIPHERAL BLOOD IN ONCOUROLOGICAL PATIENTS IN THE DISEASE DYNAMICS

Study Objectives – the study of indicators and luminol- lucigenin-dependent chemiluminescence of peripheral blood neutrophils in patients with renal cell carcinoma and bladder cancer prior to the surgery and 10 days after surgery. Held for observation of renal cell carcinoma and bladder cancer patie...

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Autores principales: L. M. Kurtasova, R. A. Zukov, E. V. Semenov
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Lenguaje:RU
Publicado: SPb RAACI 2016
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spelling oai:doaj.org-article:3b21207c12604048b676b0766ca2e18f2021-11-18T08:03:45ZFEATURES NEUTROPHIL CHEMILUMINESCENCE OF PERIPHERAL BLOOD IN ONCOUROLOGICAL PATIENTS IN THE DISEASE DYNAMICS1563-06252313-741X10.15789/1563-0625-2016-6-589-594https://doaj.org/article/3b21207c12604048b676b0766ca2e18f2016-12-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/1142https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XStudy Objectives – the study of indicators and luminol- lucigenin-dependent chemiluminescence of peripheral blood neutrophils in patients with renal cell carcinoma and bladder cancer prior to the surgery and 10 days after surgery. Held for observation of renal cell carcinoma and bladder cancer patients prior to the (n = 60) and 10 days after surgery (n = 46), aged 45-55 years. The control group consisted of 56 healthy blood donors. Luminol- and lucigenin-dependent chemiluminescence of blood neutrophils estimated De Sole et al. (1983).In patients with renal cell carcinoma and bladder cancer in blood neutrophils showed a change of the system of production of reactive oxygen species in the course of the disease. The observed changes depend on the localization of the tumor process. In patients with renal cell carcinoma changes mainly affect the primary production of reactive oxygen species in patients with bladder cancer early stages of oxidative metabolism and secondary reactive oxygen species. Restoring compensatory metabolic capacity of blood neutrophils in the postoperative period will occur in patients with bladder cancer.The findings clarify the features of the chemiluminescence response of peripheral blood neutrophils from oncourological patients that should probably be used in the development of immune rehabilitation programs in this category of patients in the postoperative period.L. M. KurtasovaR. A. ZukovE. V. SemenovSPb RAACIarticlechemiluminescenceneutrophilsreactive oxygen specieskidney cancerbladder canceroncourologyImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 18, Iss 6, Pp 589-594 (2016)
institution DOAJ
collection DOAJ
language RU
topic chemiluminescence
neutrophils
reactive oxygen species
kidney cancer
bladder cancer
oncourology
Immunologic diseases. Allergy
RC581-607
spellingShingle chemiluminescence
neutrophils
reactive oxygen species
kidney cancer
bladder cancer
oncourology
Immunologic diseases. Allergy
RC581-607
L. M. Kurtasova
R. A. Zukov
E. V. Semenov
FEATURES NEUTROPHIL CHEMILUMINESCENCE OF PERIPHERAL BLOOD IN ONCOUROLOGICAL PATIENTS IN THE DISEASE DYNAMICS
description Study Objectives – the study of indicators and luminol- lucigenin-dependent chemiluminescence of peripheral blood neutrophils in patients with renal cell carcinoma and bladder cancer prior to the surgery and 10 days after surgery. Held for observation of renal cell carcinoma and bladder cancer patients prior to the (n = 60) and 10 days after surgery (n = 46), aged 45-55 years. The control group consisted of 56 healthy blood donors. Luminol- and lucigenin-dependent chemiluminescence of blood neutrophils estimated De Sole et al. (1983).In patients with renal cell carcinoma and bladder cancer in blood neutrophils showed a change of the system of production of reactive oxygen species in the course of the disease. The observed changes depend on the localization of the tumor process. In patients with renal cell carcinoma changes mainly affect the primary production of reactive oxygen species in patients with bladder cancer early stages of oxidative metabolism and secondary reactive oxygen species. Restoring compensatory metabolic capacity of blood neutrophils in the postoperative period will occur in patients with bladder cancer.The findings clarify the features of the chemiluminescence response of peripheral blood neutrophils from oncourological patients that should probably be used in the development of immune rehabilitation programs in this category of patients in the postoperative period.
format article
author L. M. Kurtasova
R. A. Zukov
E. V. Semenov
author_facet L. M. Kurtasova
R. A. Zukov
E. V. Semenov
author_sort L. M. Kurtasova
title FEATURES NEUTROPHIL CHEMILUMINESCENCE OF PERIPHERAL BLOOD IN ONCOUROLOGICAL PATIENTS IN THE DISEASE DYNAMICS
title_short FEATURES NEUTROPHIL CHEMILUMINESCENCE OF PERIPHERAL BLOOD IN ONCOUROLOGICAL PATIENTS IN THE DISEASE DYNAMICS
title_full FEATURES NEUTROPHIL CHEMILUMINESCENCE OF PERIPHERAL BLOOD IN ONCOUROLOGICAL PATIENTS IN THE DISEASE DYNAMICS
title_fullStr FEATURES NEUTROPHIL CHEMILUMINESCENCE OF PERIPHERAL BLOOD IN ONCOUROLOGICAL PATIENTS IN THE DISEASE DYNAMICS
title_full_unstemmed FEATURES NEUTROPHIL CHEMILUMINESCENCE OF PERIPHERAL BLOOD IN ONCOUROLOGICAL PATIENTS IN THE DISEASE DYNAMICS
title_sort features neutrophil chemiluminescence of peripheral blood in oncourological patients in the disease dynamics
publisher SPb RAACI
publishDate 2016
url https://doaj.org/article/3b21207c12604048b676b0766ca2e18f
work_keys_str_mv AT lmkurtasova featuresneutrophilchemiluminescenceofperipheralbloodinoncourologicalpatientsinthediseasedynamics
AT razukov featuresneutrophilchemiluminescenceofperipheralbloodinoncourologicalpatientsinthediseasedynamics
AT evsemenov featuresneutrophilchemiluminescenceofperipheralbloodinoncourologicalpatientsinthediseasedynamics
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