Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening

Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening

Pioneer transcription factor Pax7 specifies melanotrope cells, which then allows for the binding of Tpit transcription factor. Here, authors find that while binding of heterochromatin targeting by Pax7 is independent of Tpit, Pax7-dependent chromatin opening requires Tpit.

Guardado en:
Detalles Bibliográficos
Autores principales: Alexandre Mayran, Kevin Sochodolsky, Konstantin Khetchoumian, Juliette Harris, Yves Gauthier, Amandine Bemmo, Aurelio Balsalobre, Jacques Drouin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/3b2a61a2cc2044b9be570ebc3124d40d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:3b2a61a2cc2044b9be570ebc3124d40d
record_format dspace
spelling oai:doaj.org-article:3b2a61a2cc2044b9be570ebc3124d40d2021-12-02T17:32:40ZPioneer and nonpioneer factor cooperation drives lineage specific chromatin opening10.1038/s41467-019-11791-92041-1723https://doaj.org/article/3b2a61a2cc2044b9be570ebc3124d40d2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11791-9https://doaj.org/toc/2041-1723Pioneer transcription factor Pax7 specifies melanotrope cells, which then allows for the binding of Tpit transcription factor. Here, authors find that while binding of heterochromatin targeting by Pax7 is independent of Tpit, Pax7-dependent chromatin opening requires Tpit.Alexandre MayranKevin SochodolskyKonstantin KhetchoumianJuliette HarrisYves GauthierAmandine BemmoAurelio BalsalobreJacques DrouinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alexandre Mayran
Kevin Sochodolsky
Konstantin Khetchoumian
Juliette Harris
Yves Gauthier
Amandine Bemmo
Aurelio Balsalobre
Jacques Drouin
Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening
description Pioneer transcription factor Pax7 specifies melanotrope cells, which then allows for the binding of Tpit transcription factor. Here, authors find that while binding of heterochromatin targeting by Pax7 is independent of Tpit, Pax7-dependent chromatin opening requires Tpit.
format article
author Alexandre Mayran
Kevin Sochodolsky
Konstantin Khetchoumian
Juliette Harris
Yves Gauthier
Amandine Bemmo
Aurelio Balsalobre
Jacques Drouin
author_facet Alexandre Mayran
Kevin Sochodolsky
Konstantin Khetchoumian
Juliette Harris
Yves Gauthier
Amandine Bemmo
Aurelio Balsalobre
Jacques Drouin
author_sort Alexandre Mayran
title Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening
title_short Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening
title_full Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening
title_fullStr Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening
title_full_unstemmed Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening
title_sort pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/3b2a61a2cc2044b9be570ebc3124d40d
work_keys_str_mv AT alexandremayran pioneerandnonpioneerfactorcooperationdriveslineagespecificchromatinopening
AT kevinsochodolsky pioneerandnonpioneerfactorcooperationdriveslineagespecificchromatinopening
AT konstantinkhetchoumian pioneerandnonpioneerfactorcooperationdriveslineagespecificchromatinopening
AT julietteharris pioneerandnonpioneerfactorcooperationdriveslineagespecificchromatinopening
AT yvesgauthier pioneerandnonpioneerfactorcooperationdriveslineagespecificchromatinopening
AT amandinebemmo pioneerandnonpioneerfactorcooperationdriveslineagespecificchromatinopening
AT aureliobalsalobre pioneerandnonpioneerfactorcooperationdriveslineagespecificchromatinopening
AT jacquesdrouin pioneerandnonpioneerfactorcooperationdriveslineagespecificchromatinopening
_version_ 1718380241583341568

Ejemplares similares