Bidirectional Association Between COVID-19 and Mental Health Disorders: A Narrative Review

Background: Fear, anxiety, and stress are natural reactions of the human body to unpredictable and potentially threatening conditions. Currently, individuals are encountering Coronavirus Disease 2019 (COVID-19) pandemic; it is caused by a virulent, partially unknown pathogen with high transmissibili...

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Autores principales:	Haleh Talaie, Sayed Masoud Hosseini, Maryam Nazari, Farzad Nazemi
Formato:	article
Lenguaje:	EN
Publicado:	Shaheed Beheshti University of Medical Sciences 2021
Materias:	coronavirus disease 2019 (covid-19) severe acute respiratory syndrome coronavirus 2 (sars-cov- 2) mental disorders cytokine release syndrome inflammation Medicine (General) R5-920 Toxicology. Poisons RA1190-1270
Acceso en línea:	https://doi.org/10.32598/ijmtfm.v11i3.34104 https://doaj.org/article/3b3269b45c9942d18c0138a2d5f6c233
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spelling	oai:doaj.org-article:3b3269b45c9942d18c0138a2d5f6c2332021-11-08T11:13:28ZBidirectional Association Between COVID-19 and Mental Health Disorders: A Narrative Reviewhttps://doi.org/10.32598/ijmtfm.v11i3.341042251-87622251-8770https://doaj.org/article/3b3269b45c9942d18c0138a2d5f6c2332021-08-01T00:00:00Zhttps://journals.sbmu.ac.ir/ijmtfm/article/view/34104https://doaj.org/toc/2251-8762https://doaj.org/toc/2251-8770Background: Fear, anxiety, and stress are natural reactions of the human body to unpredictable and potentially threatening conditions. Currently, individuals are encountering Coronavirus Disease 2019 (COVID-19) pandemic; it is caused by a virulent, partially unknown pathogen with high transmissibility, recognized as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It is conceivable to experience anxiety, stress, and subsequent mental health disorders during the pandemic. This narrative review provided a brief overview of mechanisms involved in COVID-19 and mental health disorders as well as the bidirectional association between them. Methods: Scientific electronic databases, such as PubMed, Scopus, Web of Science, and Google Scholar were thoroughly searched, based on different keywords in this study. Results: Lifestyle changes and isolation for breaking the chain of infection facilitate mental health disorders development more than before. Since the onset of the pandemic, the prevalence of mental health disorders has significantly increased. Moreover, studies suggested that the incidence of COVID-19 and the progression of the disease to a severe and life-threatening stage is higher in individuals with a history of mental health disorders. Inflammation is caused by, also may cause mental health disorders. Besides, COVID-19 is associated with cytokine storm and subsequent inflammation. Conclusion: There seems to be a bidirectional association between COVID-19 and mental health disorders, in which inflammation acts as an adaptor.Haleh TalaieSayed Masoud HosseiniMaryam NazariFarzad NazemiShaheed Beheshti University of Medical Sciencesarticlecoronavirus disease 2019 (covid-19)severe acute respiratory syndrome coronavirus 2 (sars-cov- 2)mental disorderscytokine release syndromeinflammationMedicine (General)R5-920Toxicology. PoisonsRA1190-1270ENInternational Journal of Medical Toxicology and Forensic Medicine, Vol 11, Iss 3, p 34101 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	coronavirus disease 2019 (covid-19) severe acute respiratory syndrome coronavirus 2 (sars-cov- 2) mental disorders cytokine release syndrome inflammation Medicine (General) R5-920 Toxicology. Poisons RA1190-1270
spellingShingle	coronavirus disease 2019 (covid-19) severe acute respiratory syndrome coronavirus 2 (sars-cov- 2) mental disorders cytokine release syndrome inflammation Medicine (General) R5-920 Toxicology. Poisons RA1190-1270 Haleh Talaie Sayed Masoud Hosseini Maryam Nazari Farzad Nazemi Bidirectional Association Between COVID-19 and Mental Health Disorders: A Narrative Review
description	Background: Fear, anxiety, and stress are natural reactions of the human body to unpredictable and potentially threatening conditions. Currently, individuals are encountering Coronavirus Disease 2019 (COVID-19) pandemic; it is caused by a virulent, partially unknown pathogen with high transmissibility, recognized as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It is conceivable to experience anxiety, stress, and subsequent mental health disorders during the pandemic. This narrative review provided a brief overview of mechanisms involved in COVID-19 and mental health disorders as well as the bidirectional association between them. Methods: Scientific electronic databases, such as PubMed, Scopus, Web of Science, and Google Scholar were thoroughly searched, based on different keywords in this study. Results: Lifestyle changes and isolation for breaking the chain of infection facilitate mental health disorders development more than before. Since the onset of the pandemic, the prevalence of mental health disorders has significantly increased. Moreover, studies suggested that the incidence of COVID-19 and the progression of the disease to a severe and life-threatening stage is higher in individuals with a history of mental health disorders. Inflammation is caused by, also may cause mental health disorders. Besides, COVID-19 is associated with cytokine storm and subsequent inflammation. Conclusion: There seems to be a bidirectional association between COVID-19 and mental health disorders, in which inflammation acts as an adaptor.
format	article
author	Haleh Talaie Sayed Masoud Hosseini Maryam Nazari Farzad Nazemi
author_facet	Haleh Talaie Sayed Masoud Hosseini Maryam Nazari Farzad Nazemi
author_sort	Haleh Talaie
title	Bidirectional Association Between COVID-19 and Mental Health Disorders: A Narrative Review
title_short	Bidirectional Association Between COVID-19 and Mental Health Disorders: A Narrative Review
title_full	Bidirectional Association Between COVID-19 and Mental Health Disorders: A Narrative Review
title_fullStr	Bidirectional Association Between COVID-19 and Mental Health Disorders: A Narrative Review
title_full_unstemmed	Bidirectional Association Between COVID-19 and Mental Health Disorders: A Narrative Review
title_sort	bidirectional association between covid-19 and mental health disorders: a narrative review
publisher	Shaheed Beheshti University of Medical Sciences
publishDate	2021
url	https://doi.org/10.32598/ijmtfm.v11i3.34104 https://doaj.org/article/3b3269b45c9942d18c0138a2d5f6c233
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Bidirectional Association Between COVID-19 and Mental Health Disorders: A Narrative Review

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