Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations

Enteropathy associated T-cell lymphoma -EATL- affects the intestine and there are two different subtypes. In this study, the authors carry out exome sequencing of the type II variant and find that it is characterized by recurrent mutations in the histone methyltransferase SETD2 that are accompanied...

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Autores principales:	Annalisa Roberti, Maria Pamela Dobay, Bettina Bisig, David Vallois, Cloé Boéchat, Evripidis Lanitis, Brigitte Bouchindhomme, Marie- Cécile Parrens, Céline Bossard, Leticia Quintanilla-Martinez, Edoardo Missiaglia, Philippe Gaulard, Laurence de Leval
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3b357026f0ad47368bed21109c34d1a3
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spelling	oai:doaj.org-article:3b357026f0ad47368bed21109c34d1a32021-12-02T15:34:50ZType II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations10.1038/ncomms126022041-1723https://doaj.org/article/3b357026f0ad47368bed21109c34d1a32016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12602https://doaj.org/toc/2041-1723Enteropathy associated T-cell lymphoma -EATL- affects the intestine and there are two different subtypes. In this study, the authors carry out exome sequencing of the type II variant and find that it is characterized by recurrent mutations in the histone methyltransferase SETD2 that are accompanied by altered H3K6 methylation.Annalisa RobertiMaria Pamela DobayBettina BisigDavid ValloisCloé BoéchatEvripidis LanitisBrigitte BouchindhommeMarie- Cécile ParrensCéline BossardLeticia Quintanilla-MartinezEdoardo MissiagliaPhilippe GaulardLaurence de LevalNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Annalisa Roberti Maria Pamela Dobay Bettina Bisig David Vallois Cloé Boéchat Evripidis Lanitis Brigitte Bouchindhomme Marie- Cécile Parrens Céline Bossard Leticia Quintanilla-Martinez Edoardo Missiaglia Philippe Gaulard Laurence de Leval Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations
description	Enteropathy associated T-cell lymphoma -EATL- affects the intestine and there are two different subtypes. In this study, the authors carry out exome sequencing of the type II variant and find that it is characterized by recurrent mutations in the histone methyltransferase SETD2 that are accompanied by altered H3K6 methylation.
format	article
author	Annalisa Roberti Maria Pamela Dobay Bettina Bisig David Vallois Cloé Boéchat Evripidis Lanitis Brigitte Bouchindhomme Marie- Cécile Parrens Céline Bossard Leticia Quintanilla-Martinez Edoardo Missiaglia Philippe Gaulard Laurence de Leval
author_facet	Annalisa Roberti Maria Pamela Dobay Bettina Bisig David Vallois Cloé Boéchat Evripidis Lanitis Brigitte Bouchindhomme Marie- Cécile Parrens Céline Bossard Leticia Quintanilla-Martinez Edoardo Missiaglia Philippe Gaulard Laurence de Leval
author_sort	Annalisa Roberti
title	Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations
title_short	Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations
title_full	Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations
title_fullStr	Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations
title_full_unstemmed	Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations
title_sort	type ii enteropathy-associated t-cell lymphoma features a unique genomic profile with highly recurrent setd2 alterations
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/3b357026f0ad47368bed21109c34d1a3
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Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations

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