Encephalitic Alphaviruses Exploit Caveola-Mediated Transcytosis at the Blood-Brain Barrier for Central Nervous System Entry

ABSTRACT Venezuelan and western equine encephalitis viruses (VEEV and WEEV, respectively) invade the central nervous system (CNS) early during infection, via neuronal and hematogenous routes. While viral replication mediates host shutoff, including expression of type I interferons (IFN), few studies...

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Bibliographic Details
Main Authors: Hamid Salimi, Matthew D. Cain, Xiaoping Jiang, Robyn A. Roth, Wandy L. Beatty, Chengqun Sun, William B. Klimstra, Jianghui Hou, Robyn S. Klein
Format: article
Language:EN
Published: American Society for Microbiology 2020
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Online Access:https://doaj.org/article/3b44feea351f4155ab631a8dee939ddc
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