Characterization of Niemann-Pick Type C2 protein expression in multiple cancers using a novel NPC2 monoclonal antibody.

Characterization of Niemann-Pick Type C2 protein expression in multiple cancers using a novel NPC2 monoclonal antibody.

Niemann-Pick Type C2 (NPC2) plays an important role in the regulation of intracellular cholesterol homeostasis via direct binding with free cholesterol. However, little is known about the significance of NPC2 in cancer. In this study, we have pinpointed the impact of various different cancers on NPC...

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Main Authors: Yi-Jen Liao, Meng-Wei Lin, Chia-Hung Yen, Yu-Ting Lin, Chung-Kwe Wang, Shiu-Feng Huang, Kuan-Hsuan Chen, Ching-Ping Yang, Tzu-Lang Chen, Ming-Feng Hou, Yi-Ming Arthur Chen
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/3b4f7bf6085b47ccba95eab8a859c50f
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