RNAi Screen and Proteomics Reveal NXF1 as a Novel Regulator of IRF5 Signaling

RNAi Screen and Proteomics Reveal NXF1 as a Novel Regulator of IRF5 Signaling

Abstract Interferon regulatory factor 5 (IRF5) is a key transcription factor of innate immunity, which plays an important role in host restriction to viral infection and inflammation. Genome-wide association studies have implied the association of IRF5 with several autoimmune diseases, including sys...

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Autores principales: Bishi Fu, Mengmeng Zhao, Lingyan Wang, Girish Patil, Jennifer A. Smith, Ignacio J. Juncadella, Ljiljana Zuvela-Jelaska, Martin E. Dorf, Shitao Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/3b52515862064e31851be11761ce05b9
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