Landscape of Carbon Ion Radiotherapy in Prostate Cancer: Clinical Application and Translational Research
Carbon ion radiotherapy (CIRT) is a useful and advanced technique for prostate cancer. This study sought to investigate the clinical efficacy and translational research for prostate cancer with carbon ion radiotherapy. We integrated the data from published articles, clinical trials websites, and our...
Guardado en:
Autores principales: | , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/3b567b448b4045bd9d7ebbeae082162b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:3b567b448b4045bd9d7ebbeae082162b |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:3b567b448b4045bd9d7ebbeae082162b2021-11-05T12:34:13ZLandscape of Carbon Ion Radiotherapy in Prostate Cancer: Clinical Application and Translational Research2234-943X10.3389/fonc.2021.760752https://doaj.org/article/3b567b448b4045bd9d7ebbeae082162b2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fonc.2021.760752/fullhttps://doaj.org/toc/2234-943XCarbon ion radiotherapy (CIRT) is a useful and advanced technique for prostate cancer. This study sought to investigate the clinical efficacy and translational research for prostate cancer with carbon ion radiotherapy. We integrated the data from published articles, clinical trials websites, and our data. The efficacy of CIRT for prostate cancer was assessed in terms of overall survival, biochemical recurrence-free survival, and toxicity response. Up to now, clinical treatment of carbon ion radiotherapy has been carried in only five countries. We found that carbon ion radiotherapy induced little genitourinary and gastrointestinal toxicity when used for prostate cancer treatment. To some extent, it led to improved outcomes in overall survival, biochemical recurrence-free survival than conventional radiotherapy, especially for high-risk prostate cancer. Carbon ion radiotherapy brought clinical benefits for prostate cancer patients, and quality of life assessment indicated that CIRT affected patients to a lesser extent. Potential biomarkers from our omics-based study could be used to predict the efficacy of prostate cancer with CIRT. Carbon ion radiotherapy brought clinical benefits for prostate cancer patients. The omics-based translational research may provide insights into individualized therapy.Xue ChenXue ChenQi YuQi YuQi YuQi YuPing LiShen FuShen FuShen FuShen FuShen FuFrontiers Media S.A.articlecarbon ion radiotherapyefficacyprostate cancerquality of lifetranslational researchNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENFrontiers in Oncology, Vol 11 (2021) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
carbon ion radiotherapy efficacy prostate cancer quality of life translational research Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
spellingShingle |
carbon ion radiotherapy efficacy prostate cancer quality of life translational research Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Xue Chen Xue Chen Qi Yu Qi Yu Qi Yu Qi Yu Ping Li Shen Fu Shen Fu Shen Fu Shen Fu Shen Fu Landscape of Carbon Ion Radiotherapy in Prostate Cancer: Clinical Application and Translational Research |
description |
Carbon ion radiotherapy (CIRT) is a useful and advanced technique for prostate cancer. This study sought to investigate the clinical efficacy and translational research for prostate cancer with carbon ion radiotherapy. We integrated the data from published articles, clinical trials websites, and our data. The efficacy of CIRT for prostate cancer was assessed in terms of overall survival, biochemical recurrence-free survival, and toxicity response. Up to now, clinical treatment of carbon ion radiotherapy has been carried in only five countries. We found that carbon ion radiotherapy induced little genitourinary and gastrointestinal toxicity when used for prostate cancer treatment. To some extent, it led to improved outcomes in overall survival, biochemical recurrence-free survival than conventional radiotherapy, especially for high-risk prostate cancer. Carbon ion radiotherapy brought clinical benefits for prostate cancer patients, and quality of life assessment indicated that CIRT affected patients to a lesser extent. Potential biomarkers from our omics-based study could be used to predict the efficacy of prostate cancer with CIRT. Carbon ion radiotherapy brought clinical benefits for prostate cancer patients. The omics-based translational research may provide insights into individualized therapy. |
format |
article |
author |
Xue Chen Xue Chen Qi Yu Qi Yu Qi Yu Qi Yu Ping Li Shen Fu Shen Fu Shen Fu Shen Fu Shen Fu |
author_facet |
Xue Chen Xue Chen Qi Yu Qi Yu Qi Yu Qi Yu Ping Li Shen Fu Shen Fu Shen Fu Shen Fu Shen Fu |
author_sort |
Xue Chen |
title |
Landscape of Carbon Ion Radiotherapy in Prostate Cancer: Clinical Application and Translational Research |
title_short |
Landscape of Carbon Ion Radiotherapy in Prostate Cancer: Clinical Application and Translational Research |
title_full |
Landscape of Carbon Ion Radiotherapy in Prostate Cancer: Clinical Application and Translational Research |
title_fullStr |
Landscape of Carbon Ion Radiotherapy in Prostate Cancer: Clinical Application and Translational Research |
title_full_unstemmed |
Landscape of Carbon Ion Radiotherapy in Prostate Cancer: Clinical Application and Translational Research |
title_sort |
landscape of carbon ion radiotherapy in prostate cancer: clinical application and translational research |
publisher |
Frontiers Media S.A. |
publishDate |
2021 |
url |
https://doaj.org/article/3b567b448b4045bd9d7ebbeae082162b |
work_keys_str_mv |
AT xuechen landscapeofcarbonionradiotherapyinprostatecancerclinicalapplicationandtranslationalresearch AT xuechen landscapeofcarbonionradiotherapyinprostatecancerclinicalapplicationandtranslationalresearch AT qiyu landscapeofcarbonionradiotherapyinprostatecancerclinicalapplicationandtranslationalresearch AT qiyu landscapeofcarbonionradiotherapyinprostatecancerclinicalapplicationandtranslationalresearch AT qiyu landscapeofcarbonionradiotherapyinprostatecancerclinicalapplicationandtranslationalresearch AT qiyu landscapeofcarbonionradiotherapyinprostatecancerclinicalapplicationandtranslationalresearch AT pingli landscapeofcarbonionradiotherapyinprostatecancerclinicalapplicationandtranslationalresearch AT shenfu landscapeofcarbonionradiotherapyinprostatecancerclinicalapplicationandtranslationalresearch AT shenfu landscapeofcarbonionradiotherapyinprostatecancerclinicalapplicationandtranslationalresearch AT shenfu landscapeofcarbonionradiotherapyinprostatecancerclinicalapplicationandtranslationalresearch AT shenfu landscapeofcarbonionradiotherapyinprostatecancerclinicalapplicationandtranslationalresearch AT shenfu landscapeofcarbonionradiotherapyinprostatecancerclinicalapplicationandtranslationalresearch |
_version_ |
1718444281401704448 |