Diagnostic and treatment of retrograde ejaculation as a manifestation of urogenital form of autonomic diabetic polyneuropathy

Background. Retrograde ejaculation in patients with type 1 diabetes mellitus is a complication of autonomic neuropathy that causes excretory infertility. It can be partial (reduction of ejaculate) or total (absence of ejaculate) and occurs in 10%–20% of men with type 1 diabetes mellitus.Aim. The aim...

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Autores principales:	Dmitry Gennadyevich Kurbatov, Gagik Radikovich Galstyan, Roman Viktorovich Rozhivanov, Aleksander Evgenyevich Lepetukhin, Yana Grigoryevna Shwarts
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2015
Materias:	retrograde ejaculation autonomic neuropathy anejaculation excretory infertility Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/3b584e79b66144cdacf81f54b0908601
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spelling	oai:doaj.org-article:3b584e79b66144cdacf81f54b09086012021-11-14T09:00:20ZDiagnostic and treatment of retrograde ejaculation as a manifestation of urogenital form of autonomic diabetic polyneuropathy2072-03512072-037810.14341/DM2015393-98https://doaj.org/article/3b584e79b66144cdacf81f54b09086012015-10-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6869https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Background. Retrograde ejaculation in patients with type 1 diabetes mellitus is a complication of autonomic neuropathy that causes excretory infertility. It can be partial (reduction of ejaculate) or total (absence of ejaculate) and occurs in 10%–20% of men with type 1 diabetes mellitus.Aim. The aim of the study was to assess the effectiveness of a new endoscopic method for retrograde ejaculation correction and antegrade ejaculation restoration.Materials and methods. We included 30 patients with type 1 diabetes mellitus who had spermatozoa present in their post-orgasmic urine and ultrasonographic evidence of impaired or absent bladder neck closure. The mean age of participants was 32 (30–35) years, mean duration of diabetes was 17 (12–22) years and mean preoperative glycated haemoglobin level was 7.4% (6.9%–8.0%). All participants had total retrograde ejaculation. We used conventional irrigated urethrocystoscopy under local anaesthesia. During urethroscopy, bladder neck gaping was observed in all cases. Biocompatible material was injected at three points under the mucous layer of the posterior urethra, reaching the closing of the opposite edges of the urethra. A spermiogram was examined 1 week after the operation.Results. Restoration of antegrade ejaculation was achieved for 22 patients (73%), and the effects persisted for a mean of 7 (2–12) months. The spouses of four men became pregnant after surgery. In one case, the pregnancy resulted in a spontaneous abortion at gestational week 8, but the other three cases continued normally.Conclusion.This new method provides a highly effective means of restoring the physiological passage of the ejaculate. The operation is a low-invasive endoscopic procedure that does not disrupt urination, and it is possible to receive ejaculate of sufficient.Dmitry Gennadyevich KurbatovGagik Radikovich GalstyanRoman Viktorovich RozhivanovAleksander Evgenyevich LepetukhinYana Grigoryevna ShwartsEndocrinology Research Centrearticleretrograde ejaculationautonomic neuropathyanejaculationexcretory infertilityNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 18, Iss 3, Pp 93-98 (2015)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	retrograde ejaculation autonomic neuropathy anejaculation excretory infertility Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	retrograde ejaculation autonomic neuropathy anejaculation excretory infertility Nutritional diseases. Deficiency diseases RC620-627 Dmitry Gennadyevich Kurbatov Gagik Radikovich Galstyan Roman Viktorovich Rozhivanov Aleksander Evgenyevich Lepetukhin Yana Grigoryevna Shwarts Diagnostic and treatment of retrograde ejaculation as a manifestation of urogenital form of autonomic diabetic polyneuropathy
description	Background. Retrograde ejaculation in patients with type 1 diabetes mellitus is a complication of autonomic neuropathy that causes excretory infertility. It can be partial (reduction of ejaculate) or total (absence of ejaculate) and occurs in 10%–20% of men with type 1 diabetes mellitus.Aim. The aim of the study was to assess the effectiveness of a new endoscopic method for retrograde ejaculation correction and antegrade ejaculation restoration.Materials and methods. We included 30 patients with type 1 diabetes mellitus who had spermatozoa present in their post-orgasmic urine and ultrasonographic evidence of impaired or absent bladder neck closure. The mean age of participants was 32 (30–35) years, mean duration of diabetes was 17 (12–22) years and mean preoperative glycated haemoglobin level was 7.4% (6.9%–8.0%). All participants had total retrograde ejaculation. We used conventional irrigated urethrocystoscopy under local anaesthesia. During urethroscopy, bladder neck gaping was observed in all cases. Biocompatible material was injected at three points under the mucous layer of the posterior urethra, reaching the closing of the opposite edges of the urethra. A spermiogram was examined 1 week after the operation.Results. Restoration of antegrade ejaculation was achieved for 22 patients (73%), and the effects persisted for a mean of 7 (2–12) months. The spouses of four men became pregnant after surgery. In one case, the pregnancy resulted in a spontaneous abortion at gestational week 8, but the other three cases continued normally.Conclusion.This new method provides a highly effective means of restoring the physiological passage of the ejaculate. The operation is a low-invasive endoscopic procedure that does not disrupt urination, and it is possible to receive ejaculate of sufficient.
format	article
author	Dmitry Gennadyevich Kurbatov Gagik Radikovich Galstyan Roman Viktorovich Rozhivanov Aleksander Evgenyevich Lepetukhin Yana Grigoryevna Shwarts
author_facet	Dmitry Gennadyevich Kurbatov Gagik Radikovich Galstyan Roman Viktorovich Rozhivanov Aleksander Evgenyevich Lepetukhin Yana Grigoryevna Shwarts
author_sort	Dmitry Gennadyevich Kurbatov
title	Diagnostic and treatment of retrograde ejaculation as a manifestation of urogenital form of autonomic diabetic polyneuropathy
title_short	Diagnostic and treatment of retrograde ejaculation as a manifestation of urogenital form of autonomic diabetic polyneuropathy
title_full	Diagnostic and treatment of retrograde ejaculation as a manifestation of urogenital form of autonomic diabetic polyneuropathy
title_fullStr	Diagnostic and treatment of retrograde ejaculation as a manifestation of urogenital form of autonomic diabetic polyneuropathy
title_full_unstemmed	Diagnostic and treatment of retrograde ejaculation as a manifestation of urogenital form of autonomic diabetic polyneuropathy
title_sort	diagnostic and treatment of retrograde ejaculation as a manifestation of urogenital form of autonomic diabetic polyneuropathy
publisher	Endocrinology Research Centre
publishDate	2015
url	https://doaj.org/article/3b584e79b66144cdacf81f54b0908601
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Diagnostic and treatment of retrograde ejaculation as a manifestation of urogenital form of autonomic diabetic polyneuropathy

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