Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones
Axially chiral arylquinazolinones are structural motifs in several natural products and can also act as chiral ligands. Here, the authors show a chiral phosphoric acid-catalysed strategy to access enantiomerically pure arylquinazolinones by efficient transfer of central chirality into axial chiralit...
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2017
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oai:doaj.org-article:3b59fe05320b44a1be60dbb3f7de7f2f2021-12-02T14:42:25ZBrønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones10.1038/ncomms154892041-1723https://doaj.org/article/3b59fe05320b44a1be60dbb3f7de7f2f2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15489https://doaj.org/toc/2041-1723Axially chiral arylquinazolinones are structural motifs in several natural products and can also act as chiral ligands. Here, the authors show a chiral phosphoric acid-catalysed strategy to access enantiomerically pure arylquinazolinones by efficient transfer of central chirality into axial chirality.Yong-Bin WangSheng-Cai ZhengYu-Mei HuBin TanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
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Science Q Yong-Bin Wang Sheng-Cai Zheng Yu-Mei Hu Bin Tan Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones |
description |
Axially chiral arylquinazolinones are structural motifs in several natural products and can also act as chiral ligands. Here, the authors show a chiral phosphoric acid-catalysed strategy to access enantiomerically pure arylquinazolinones by efficient transfer of central chirality into axial chirality. |
format |
article |
author |
Yong-Bin Wang Sheng-Cai Zheng Yu-Mei Hu Bin Tan |
author_facet |
Yong-Bin Wang Sheng-Cai Zheng Yu-Mei Hu Bin Tan |
author_sort |
Yong-Bin Wang |
title |
Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones |
title_short |
Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones |
title_full |
Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones |
title_fullStr |
Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones |
title_full_unstemmed |
Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones |
title_sort |
brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/3b59fe05320b44a1be60dbb3f7de7f2f |
work_keys_str_mv |
AT yongbinwang brønstedacidcatalysedenantioselectiveconstructionofaxiallychiralarylquinazolinones AT shengcaizheng brønstedacidcatalysedenantioselectiveconstructionofaxiallychiralarylquinazolinones AT yumeihu brønstedacidcatalysedenantioselectiveconstructionofaxiallychiralarylquinazolinones AT bintan brønstedacidcatalysedenantioselectiveconstructionofaxiallychiralarylquinazolinones |
_version_ |
1718389682603032576 |