Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones

Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones

Axially chiral arylquinazolinones are structural motifs in several natural products and can also act as chiral ligands. Here, the authors show a chiral phosphoric acid-catalysed strategy to access enantiomerically pure arylquinazolinones by efficient transfer of central chirality into axial chiralit...

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Main Authors: Yong-Bin Wang, Sheng-Cai Zheng, Yu-Mei Hu, Bin Tan
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Science
Q
Online Access:https://doaj.org/article/3b59fe05320b44a1be60dbb3f7de7f2f
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spelling oai:doaj.org-article:3b59fe05320b44a1be60dbb3f7de7f2f2021-12-02T14:42:25ZBrønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones10.1038/ncomms154892041-1723https://doaj.org/article/3b59fe05320b44a1be60dbb3f7de7f2f2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15489https://doaj.org/toc/2041-1723Axially chiral arylquinazolinones are structural motifs in several natural products and can also act as chiral ligands. Here, the authors show a chiral phosphoric acid-catalysed strategy to access enantiomerically pure arylquinazolinones by efficient transfer of central chirality into axial chirality.Yong-Bin WangSheng-Cai ZhengYu-Mei HuBin TanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yong-Bin Wang
Sheng-Cai Zheng
Yu-Mei Hu
Bin Tan
Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones
description Axially chiral arylquinazolinones are structural motifs in several natural products and can also act as chiral ligands. Here, the authors show a chiral phosphoric acid-catalysed strategy to access enantiomerically pure arylquinazolinones by efficient transfer of central chirality into axial chirality.
format article
author Yong-Bin Wang
Sheng-Cai Zheng
Yu-Mei Hu
Bin Tan
author_facet Yong-Bin Wang
Sheng-Cai Zheng
Yu-Mei Hu
Bin Tan
author_sort Yong-Bin Wang
title Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones
title_short Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones
title_full Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones
title_fullStr Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones
title_full_unstemmed Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones
title_sort brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/3b59fe05320b44a1be60dbb3f7de7f2f
work_keys_str_mv AT yongbinwang brønstedacidcatalysedenantioselectiveconstructionofaxiallychiralarylquinazolinones
AT shengcaizheng brønstedacidcatalysedenantioselectiveconstructionofaxiallychiralarylquinazolinones
AT yumeihu brønstedacidcatalysedenantioselectiveconstructionofaxiallychiralarylquinazolinones
AT bintan brønstedacidcatalysedenantioselectiveconstructionofaxiallychiralarylquinazolinones
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