Management of oxidative stress in animals using preparation based on Trametes pubescens

It has been determined that exposure to different stressors is associated with the development of oxidative stress, both in animals and in humans. The antioxidant defense system resists the development of oxidative stress. Basidiomycetes are the producers of a variety of biologically active compound...

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Autores principales:	L. I. Kolesnikova, E. D. Romanova, V. A. Chkhenkeli, M. A. Darenskaya, L. A. Grebenkina, S. I. Kolesnikov
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2018
Materias:	oxidative stress antioxidants stress animals Science Q
Acceso en línea:	https://doaj.org/article/3b72e45613b941deae6c452c8148215e
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spelling	oai:doaj.org-article:3b72e45613b941deae6c452c8148215e2021-11-23T06:14:39ZManagement of oxidative stress in animals using preparation based on Trametes pubescens2541-94202587-959610.29413/ABS.2018-3.1.19https://doaj.org/article/3b72e45613b941deae6c452c8148215e2018-02-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/548https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596It has been determined that exposure to different stressors is associated with the development of oxidative stress, both in animals and in humans. The antioxidant defense system resists the development of oxidative stress. Basidiomycetes are the producers of a variety of biologically active compounds, including triterpene acids, exopolysaccharides, etc. Products derived from these species have immunostimulating, antitumor, antioxidant, antimetastatic action, and are effective for liver diseases treatment. The aim of the study, was to determine the antioxidant activity of Trametin to limit the stress-induced lipid peroxidation process. Antioxidant properties of Trametin (a product obtained by liquid-phase cultivation of the xylotroph fungus Trametes pubescens) were studied under experimental stress (decrease of the lighting intensity in piglets). 1t has been found that Trametin serves as an effective prevention of oxidative stress in stress conditions. 1t increases the level of unsaturation of lipids, reduces the concentration of primary and end products of lipid peroxidation, and also increases the total antioxidant activity of the blood, the activity of superoxide dismutase and reduces the glutathione level. Thus, the study of the effect of the preparation obtained by liquid-phase fermentation from fungus xylotroph of the genus Trametes pubescens showed a pronounced antioxidant effect on the model of dark stress in experimental animals, which can serve as a basis for its further application in veterinary and clinical medicine.L. I. KolesnikovaE. D. RomanovaV. A. ChkhenkeliM. A. DarenskayaL. A. GrebenkinaS. I. KolesnikovScientific Сentre for Family Health and Human Reproduction Problemsarticleoxidative stressantioxidantsstressanimalsScienceQRUActa Biomedica Scientifica, Vol 3, Iss 1, Pp 120-124 (2018)
institution	DOAJ
collection	DOAJ
language	RU
topic	oxidative stress antioxidants stress animals Science Q
spellingShingle	oxidative stress antioxidants stress animals Science Q L. I. Kolesnikova E. D. Romanova V. A. Chkhenkeli M. A. Darenskaya L. A. Grebenkina S. I. Kolesnikov Management of oxidative stress in animals using preparation based on Trametes pubescens
description	It has been determined that exposure to different stressors is associated with the development of oxidative stress, both in animals and in humans. The antioxidant defense system resists the development of oxidative stress. Basidiomycetes are the producers of a variety of biologically active compounds, including triterpene acids, exopolysaccharides, etc. Products derived from these species have immunostimulating, antitumor, antioxidant, antimetastatic action, and are effective for liver diseases treatment. The aim of the study, was to determine the antioxidant activity of Trametin to limit the stress-induced lipid peroxidation process. Antioxidant properties of Trametin (a product obtained by liquid-phase cultivation of the xylotroph fungus Trametes pubescens) were studied under experimental stress (decrease of the lighting intensity in piglets). 1t has been found that Trametin serves as an effective prevention of oxidative stress in stress conditions. 1t increases the level of unsaturation of lipids, reduces the concentration of primary and end products of lipid peroxidation, and also increases the total antioxidant activity of the blood, the activity of superoxide dismutase and reduces the glutathione level. Thus, the study of the effect of the preparation obtained by liquid-phase fermentation from fungus xylotroph of the genus Trametes pubescens showed a pronounced antioxidant effect on the model of dark stress in experimental animals, which can serve as a basis for its further application in veterinary and clinical medicine.
format	article
author	L. I. Kolesnikova E. D. Romanova V. A. Chkhenkeli M. A. Darenskaya L. A. Grebenkina S. I. Kolesnikov
author_facet	L. I. Kolesnikova E. D. Romanova V. A. Chkhenkeli M. A. Darenskaya L. A. Grebenkina S. I. Kolesnikov
author_sort	L. I. Kolesnikova
title	Management of oxidative stress in animals using preparation based on Trametes pubescens
title_short	Management of oxidative stress in animals using preparation based on Trametes pubescens
title_full	Management of oxidative stress in animals using preparation based on Trametes pubescens
title_fullStr	Management of oxidative stress in animals using preparation based on Trametes pubescens
title_full_unstemmed	Management of oxidative stress in animals using preparation based on Trametes pubescens
title_sort	management of oxidative stress in animals using preparation based on trametes pubescens
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2018
url	https://doaj.org/article/3b72e45613b941deae6c452c8148215e
work_keys_str_mv	AT likolesnikova managementofoxidativestressinanimalsusingpreparationbasedontrametespubescens AT edromanova managementofoxidativestressinanimalsusingpreparationbasedontrametespubescens AT vachkhenkeli managementofoxidativestressinanimalsusingpreparationbasedontrametespubescens AT madarenskaya managementofoxidativestressinanimalsusingpreparationbasedontrametespubescens AT lagrebenkina managementofoxidativestressinanimalsusingpreparationbasedontrametespubescens AT sikolesnikov managementofoxidativestressinanimalsusingpreparationbasedontrametespubescens
_version_	1718416998866616320

Management of oxidative stress in animals using preparation based on Trametes pubescens

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