Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data

Estimating direct and indirect genetic effects on offspring phenotypes using genome-wide summary results data

Estimating direct and indirect effects of genotypes on phenotypes is important for genetic analyses such as Mendelian randomization. Here the authors compare five different methods to estimate direct and indirect genetic effects using summary results statistics that account for sample overlap.

Guardado en:
Detalles Bibliográficos
Autores principales: Nicole M. Warrington, Liang-Dar Hwang, Michel G. Nivard, David M. Evans
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/3b86a242695944458fd715e56be7d963
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares