Rhythmic potassium transport regulates the circadian clock in human red blood cells

Circadian rhythms usually rely on cyclic variations in gene expression. Red blood cells, however, display circadian rhythms while being devoid of nuclear DNA. Here, Henslee and colleagues show that circadian rhythms in isolated human red blood cells are dependent on rhythmic transport of K+ ions.

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Autores principales:	Erin A. Henslee, Priya Crosby, Stephen J. Kitcatt, Jack S. W. Parry, Andrea Bernardini, Rula G. Abdallat, Gabriella Braun, Henry O. Fatoyinbo, Esther J. Harrison, Rachel S. Edgar, Kai F. Hoettges, Akhilesh B. Reddy, Rita I. Jabr, Malcolm von Schantz, John S. O’Neill, Fatima H. Labeed
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3b9cc98ebe9f4f4a828664161f701abc
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spelling	oai:doaj.org-article:3b9cc98ebe9f4f4a828664161f701abc2021-12-02T14:40:36ZRhythmic potassium transport regulates the circadian clock in human red blood cells10.1038/s41467-017-02161-42041-1723https://doaj.org/article/3b9cc98ebe9f4f4a828664161f701abc2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02161-4https://doaj.org/toc/2041-1723Circadian rhythms usually rely on cyclic variations in gene expression. Red blood cells, however, display circadian rhythms while being devoid of nuclear DNA. Here, Henslee and colleagues show that circadian rhythms in isolated human red blood cells are dependent on rhythmic transport of K+ ions.Erin A. HensleePriya CrosbyStephen J. KitcattJack S. W. ParryAndrea BernardiniRula G. AbdallatGabriella BraunHenry O. FatoyinboEsther J. HarrisonRachel S. EdgarKai F. HoettgesAkhilesh B. ReddyRita I. JabrMalcolm von SchantzJohn S. O’NeillFatima H. LabeedNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Erin A. Henslee Priya Crosby Stephen J. Kitcatt Jack S. W. Parry Andrea Bernardini Rula G. Abdallat Gabriella Braun Henry O. Fatoyinbo Esther J. Harrison Rachel S. Edgar Kai F. Hoettges Akhilesh B. Reddy Rita I. Jabr Malcolm von Schantz John S. O’Neill Fatima H. Labeed Rhythmic potassium transport regulates the circadian clock in human red blood cells
description	Circadian rhythms usually rely on cyclic variations in gene expression. Red blood cells, however, display circadian rhythms while being devoid of nuclear DNA. Here, Henslee and colleagues show that circadian rhythms in isolated human red blood cells are dependent on rhythmic transport of K+ ions.
format	article
author	Erin A. Henslee Priya Crosby Stephen J. Kitcatt Jack S. W. Parry Andrea Bernardini Rula G. Abdallat Gabriella Braun Henry O. Fatoyinbo Esther J. Harrison Rachel S. Edgar Kai F. Hoettges Akhilesh B. Reddy Rita I. Jabr Malcolm von Schantz John S. O’Neill Fatima H. Labeed
author_facet	Erin A. Henslee Priya Crosby Stephen J. Kitcatt Jack S. W. Parry Andrea Bernardini Rula G. Abdallat Gabriella Braun Henry O. Fatoyinbo Esther J. Harrison Rachel S. Edgar Kai F. Hoettges Akhilesh B. Reddy Rita I. Jabr Malcolm von Schantz John S. O’Neill Fatima H. Labeed
author_sort	Erin A. Henslee
title	Rhythmic potassium transport regulates the circadian clock in human red blood cells
title_short	Rhythmic potassium transport regulates the circadian clock in human red blood cells
title_full	Rhythmic potassium transport regulates the circadian clock in human red blood cells
title_fullStr	Rhythmic potassium transport regulates the circadian clock in human red blood cells
title_full_unstemmed	Rhythmic potassium transport regulates the circadian clock in human red blood cells
title_sort	rhythmic potassium transport regulates the circadian clock in human red blood cells
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/3b9cc98ebe9f4f4a828664161f701abc
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Rhythmic potassium transport regulates the circadian clock in human red blood cells

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