The role of haematological parameters in predicting the response to radical chemoradiotherapy in patients with anal squamous cell cancer

Historically, the treatment of choice for anal cancer had been abdominoperineal resection (APR). Radical radiotherapy with concurrent 5-fluorouracil plus mitomycin C chemotherapy was later established as standard therapy, although with a failure rate of 20–30%. The aim of this study was to evaluate...

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Autores principales: Stojanovic-Rundic Suzana, Marinkovic Mladen, Cavic Milena, Karapandzic Vesna Plesinac, Gavrilovic Dusica, Jankovic Radmila, de Voer Richarda M., Castellvi-Bel Sergi, Krivokapic Zoran
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Publicado: Sciendo 2021
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Acceso en línea:https://doaj.org/article/3b9d2dfea9064ae09dc181fefa74200f
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spelling oai:doaj.org-article:3b9d2dfea9064ae09dc181fefa74200f2021-12-05T14:11:10ZThe role of haematological parameters in predicting the response to radical chemoradiotherapy in patients with anal squamous cell cancer1581-320710.2478/raon-2021-0039https://doaj.org/article/3b9d2dfea9064ae09dc181fefa74200f2021-10-01T00:00:00Zhttps://doi.org/10.2478/raon-2021-0039https://doaj.org/toc/1581-3207Historically, the treatment of choice for anal cancer had been abdominoperineal resection (APR). Radical radiotherapy with concurrent 5-fluorouracil plus mitomycin C chemotherapy was later established as standard therapy, although with a failure rate of 20–30%. The aim of this study was to evaluate the outcomes after radical chemoradiotherapy (CRT), prognostic and predictive factors and patterns of failure.Stojanovic-Rundic SuzanaMarinkovic MladenCavic MilenaKarapandzic Vesna PlesinacGavrilovic DusicaJankovic Radmilade Voer Richarda M.Castellvi-Bel SergiKrivokapic ZoranSciendoarticleanal cancerchemoradiotherapyhaematological parametersMedical physics. Medical radiology. Nuclear medicineR895-920ENRadiology and Oncology, Vol 55, Iss 4, Pp 449-458 (2021)
institution DOAJ
collection DOAJ
language EN
topic anal cancer
chemoradiotherapy
haematological parameters
Medical physics. Medical radiology. Nuclear medicine
R895-920
spellingShingle anal cancer
chemoradiotherapy
haematological parameters
Medical physics. Medical radiology. Nuclear medicine
R895-920
Stojanovic-Rundic Suzana
Marinkovic Mladen
Cavic Milena
Karapandzic Vesna Plesinac
Gavrilovic Dusica
Jankovic Radmila
de Voer Richarda M.
Castellvi-Bel Sergi
Krivokapic Zoran
The role of haematological parameters in predicting the response to radical chemoradiotherapy in patients with anal squamous cell cancer
description Historically, the treatment of choice for anal cancer had been abdominoperineal resection (APR). Radical radiotherapy with concurrent 5-fluorouracil plus mitomycin C chemotherapy was later established as standard therapy, although with a failure rate of 20–30%. The aim of this study was to evaluate the outcomes after radical chemoradiotherapy (CRT), prognostic and predictive factors and patterns of failure.
format article
author Stojanovic-Rundic Suzana
Marinkovic Mladen
Cavic Milena
Karapandzic Vesna Plesinac
Gavrilovic Dusica
Jankovic Radmila
de Voer Richarda M.
Castellvi-Bel Sergi
Krivokapic Zoran
author_facet Stojanovic-Rundic Suzana
Marinkovic Mladen
Cavic Milena
Karapandzic Vesna Plesinac
Gavrilovic Dusica
Jankovic Radmila
de Voer Richarda M.
Castellvi-Bel Sergi
Krivokapic Zoran
author_sort Stojanovic-Rundic Suzana
title The role of haematological parameters in predicting the response to radical chemoradiotherapy in patients with anal squamous cell cancer
title_short The role of haematological parameters in predicting the response to radical chemoradiotherapy in patients with anal squamous cell cancer
title_full The role of haematological parameters in predicting the response to radical chemoradiotherapy in patients with anal squamous cell cancer
title_fullStr The role of haematological parameters in predicting the response to radical chemoradiotherapy in patients with anal squamous cell cancer
title_full_unstemmed The role of haematological parameters in predicting the response to radical chemoradiotherapy in patients with anal squamous cell cancer
title_sort role of haematological parameters in predicting the response to radical chemoradiotherapy in patients with anal squamous cell cancer
publisher Sciendo
publishDate 2021
url https://doaj.org/article/3b9d2dfea9064ae09dc181fefa74200f
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