Urobiome: An outlook on the metagenome of urological diseases

The urinary tract likely plays a role in the development of various urinary diseases due to the recently recognized notion that urine is not sterile. In this mini review, we summarize the current literature regarding the urinary microbiome and mycobiome and its relationship to various urinary diseas...

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Autores principales:	Rachel Shoemaker, Jayoung Kim
Formato:	article
Lenguaje:	EN
Publicado:	Korean Urological Association 2021
Materias:	microbiome mycobiome urology Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/3b9dd5898509434a8161189accd3ef12
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spelling	oai:doaj.org-article:3b9dd5898509434a8161189accd3ef122021-11-10T02:48:04ZUrobiome: An outlook on the metagenome of urological diseases10.4111/icu.202103122466-04932466-054Xhttps://doaj.org/article/3b9dd5898509434a8161189accd3ef122021-11-01T00:00:00Zhttps://icurology.org/pdf/10.4111/icu.20210312https://doaj.org/toc/2466-0493https://doaj.org/toc/2466-054XThe urinary tract likely plays a role in the development of various urinary diseases due to the recently recognized notion that urine is not sterile. In this mini review, we summarize the current literature regarding the urinary microbiome and mycobiome and its relationship to various urinary diseases. It has been recently discovered that the healthy urinary tract contains a host of microorganisms, creating a urinary microbiome. The relative abundance and type of bacteria varies, but generally, deviations in the standard microbiome are observed in individuals with urologic diseases, such as bladder cancer, benign prostatic hyperplasia, urgency urinary incontinence, overactive bladder syndrome, interstitial cystitis, bladder pain syndrome, and urinary tract infections. However, whether this change is causative, or correlative has yet to be determined. In summary, the urinary tract hosts a complex microbiome. Changes in this microbiome may be indicative of urologic diseases and can be tracked to predict, prevent, and treat them in individuals. However, current analytical and sampling collection methods may present limitations to the development in the understanding of the urinary microbiome and its relationship with various urinary diseases. Further research on the differences between healthy and diseased microbiomes, the long-term effects of antibiotic treatments on the urobiome, and the effect of the urinary mycobiome on general health will be important in developing a comprehensive understanding of the urinary microbiome and its relationship to the human body.Rachel ShoemakerJayoung KimKorean Urological AssociationarticlemicrobiomemycobiomeurologyDiseases of the genitourinary system. UrologyRC870-923ENInvestigative and Clinical Urology, Vol 62, Iss 6, Pp 611-622 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	microbiome mycobiome urology Diseases of the genitourinary system. Urology RC870-923
spellingShingle	microbiome mycobiome urology Diseases of the genitourinary system. Urology RC870-923 Rachel Shoemaker Jayoung Kim Urobiome: An outlook on the metagenome of urological diseases
description	The urinary tract likely plays a role in the development of various urinary diseases due to the recently recognized notion that urine is not sterile. In this mini review, we summarize the current literature regarding the urinary microbiome and mycobiome and its relationship to various urinary diseases. It has been recently discovered that the healthy urinary tract contains a host of microorganisms, creating a urinary microbiome. The relative abundance and type of bacteria varies, but generally, deviations in the standard microbiome are observed in individuals with urologic diseases, such as bladder cancer, benign prostatic hyperplasia, urgency urinary incontinence, overactive bladder syndrome, interstitial cystitis, bladder pain syndrome, and urinary tract infections. However, whether this change is causative, or correlative has yet to be determined. In summary, the urinary tract hosts a complex microbiome. Changes in this microbiome may be indicative of urologic diseases and can be tracked to predict, prevent, and treat them in individuals. However, current analytical and sampling collection methods may present limitations to the development in the understanding of the urinary microbiome and its relationship with various urinary diseases. Further research on the differences between healthy and diseased microbiomes, the long-term effects of antibiotic treatments on the urobiome, and the effect of the urinary mycobiome on general health will be important in developing a comprehensive understanding of the urinary microbiome and its relationship to the human body.
format	article
author	Rachel Shoemaker Jayoung Kim
author_facet	Rachel Shoemaker Jayoung Kim
author_sort	Rachel Shoemaker
title	Urobiome: An outlook on the metagenome of urological diseases
title_short	Urobiome: An outlook on the metagenome of urological diseases
title_full	Urobiome: An outlook on the metagenome of urological diseases
title_fullStr	Urobiome: An outlook on the metagenome of urological diseases
title_full_unstemmed	Urobiome: An outlook on the metagenome of urological diseases
title_sort	urobiome: an outlook on the metagenome of urological diseases
publisher	Korean Urological Association
publishDate	2021
url	https://doaj.org/article/3b9dd5898509434a8161189accd3ef12
work_keys_str_mv	AT rachelshoemaker urobiomeanoutlookonthemetagenomeofurologicaldiseases AT jayoungkim urobiomeanoutlookonthemetagenomeofurologicaldiseases
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Urobiome: An outlook on the metagenome of urological diseases

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