Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy

Cassandra C Brooks, 1 Sayena Jabbehdari, 1, 2 Preeya K Gupta 1 1Department of Ophthalmology, Duke University Eye Center, Durham, NC, USA; 2Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USACorrespondence: Preeya K GuptaDepartment of Ophthalmology,...

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Autores principales:	Brooks CC, Jabbehdari S, Gupta PK
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	dexamethasone sustained-release intracanalicular ocular inflammation ocular pain ophthalmic surgery Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/3ba014f7096b478a85253e9232f07bfe
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spelling	oai:doaj.org-article:3ba014f7096b478a85253e9232f07bfe2021-12-02T12:13:41ZDexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy1177-5483https://doaj.org/article/3ba014f7096b478a85253e9232f07bfe2020-01-01T00:00:00Zhttps://www.dovepress.com/dexamethasone-04mg-sustained-release-intracanalicular-insert-in-the-ma-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Cassandra C Brooks, 1 Sayena Jabbehdari, 1, 2 Preeya K Gupta 1 1Department of Ophthalmology, Duke University Eye Center, Durham, NC, USA; 2Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USACorrespondence: Preeya K GuptaDepartment of Ophthalmology, Duke University Eye Center, 4709 Creekstone Drive, Suite 100, Durham, NC 27703, USATel +1 919 660-5234Fax +1 919 660-5070Email preeya.gupta@duke.eduAbstract: Inflammation and pain are two prevalent findings after ocular surgery. Corticosteroids are widely administrated as a core treatment to control post-surgical inflammation and pain. Improper patient adherence to post-operative eye drop regimens, limited bioavailability of topical eye drops, and the negative impact of preservatives used in many of these eye drops, has made a strong case for novel therapies in the treatment of post-operative pain and inflammation. This review of the literature will focus on the role of intracanalicular sustained-release dexamethasone (Dextenza, Ocular Therapeutix, Bedford, MA, USA) for the management of ocular inflammation and pain.Keywords: dexamethasone, sustained-release, intracanalicular, ocular inflammation, ocular pain, ophthalmic surgeryBrooks CCJabbehdari SGupta PKDove Medical Pressarticledexamethasonesustained-releaseintracanalicularocular inflammationocular painophthalmic surgeryOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 89-94 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	dexamethasone sustained-release intracanalicular ocular inflammation ocular pain ophthalmic surgery Ophthalmology RE1-994
spellingShingle	dexamethasone sustained-release intracanalicular ocular inflammation ocular pain ophthalmic surgery Ophthalmology RE1-994 Brooks CC Jabbehdari S Gupta PK Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy
description	Cassandra C Brooks, 1 Sayena Jabbehdari, 1, 2 Preeya K Gupta 1 1Department of Ophthalmology, Duke University Eye Center, Durham, NC, USA; 2Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USACorrespondence: Preeya K GuptaDepartment of Ophthalmology, Duke University Eye Center, 4709 Creekstone Drive, Suite 100, Durham, NC 27703, USATel +1 919 660-5234Fax +1 919 660-5070Email preeya.gupta@duke.eduAbstract: Inflammation and pain are two prevalent findings after ocular surgery. Corticosteroids are widely administrated as a core treatment to control post-surgical inflammation and pain. Improper patient adherence to post-operative eye drop regimens, limited bioavailability of topical eye drops, and the negative impact of preservatives used in many of these eye drops, has made a strong case for novel therapies in the treatment of post-operative pain and inflammation. This review of the literature will focus on the role of intracanalicular sustained-release dexamethasone (Dextenza, Ocular Therapeutix, Bedford, MA, USA) for the management of ocular inflammation and pain.Keywords: dexamethasone, sustained-release, intracanalicular, ocular inflammation, ocular pain, ophthalmic surgery
format	article
author	Brooks CC Jabbehdari S Gupta PK
author_facet	Brooks CC Jabbehdari S Gupta PK
author_sort	Brooks CC
title	Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy
title_short	Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy
title_full	Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy
title_fullStr	Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy
title_full_unstemmed	Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy
title_sort	dexamethasone 0.4mg sustained-release intracanalicular insert in the management of ocular inflammation and pain following ophthalmic surgery: design, development and place in therapy
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/3ba014f7096b478a85253e9232f07bfe
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Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy

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