Mouse PRDM9 DNA-binding specificity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombination.

Mouse PRDM9 DNA-binding specificity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombination.

Meiotic recombination generates reciprocal exchanges between homologous chromosomes (also called crossovers, COs) that are essential for proper chromosome segregation during meiosis and are a major source of genome diversity by generating new allele combinations. COs have two striking properties: th...

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Autores principales: Corinne Grey, Pauline Barthès, Gaëlle Chauveau-Le Friec, Francina Langa, Frédéric Baudat, Bernard de Massy
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/3ba0c3f951d740a3beea6fcdfa7c67d7
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