The role of medial prefrontal cortex in the working memory maintenance of one’s own emotional responses

Abstract The role of medial prefrontal cortex (MPFC) in maintaining emotional information within working memory (WM) remains insufficiently investigated – with some studies suggesting this process activates MPFC and others suggesting its activity is suppressed. To reconcile these different results,...

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Autores principales:	Ryan Smith, Richard D. Lane, Anna Alkozei, Jennifer Bao, Courtney Smith, Anna Sanova, Matthew Nettles, William D. S. Killgore
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/3ba6237a50f24a49b5589856868cfe01
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spelling	oai:doaj.org-article:3ba6237a50f24a49b5589856868cfe012021-12-02T11:40:26ZThe role of medial prefrontal cortex in the working memory maintenance of one’s own emotional responses10.1038/s41598-018-21896-82045-2322https://doaj.org/article/3ba6237a50f24a49b5589856868cfe012018-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-21896-8https://doaj.org/toc/2045-2322Abstract The role of medial prefrontal cortex (MPFC) in maintaining emotional information within working memory (WM) remains insufficiently investigated – with some studies suggesting this process activates MPFC and others suggesting its activity is suppressed. To reconcile these different results, we asked 26 healthy participants to complete a WM task involving the maintenance of emotional content (EWM), visual content (VWM), or no content (“rest”) after exposure to emotion-provoking images. We also assessed individual differences in emotional awareness (EA). We observed that dorsal MPFC was more active during EWM than VWM; further, relative to the rest condition, both of these WM conditions involved suppression of ventral MPFC. We also observed that the dorsal anterior cingulate subregion of dorsal MPFC was positively associated with EA. We discuss how these results may be able to reconcile the findings of previous EWM studies, and extend understanding of the relationship between MPFC, EA, and WM.Ryan SmithRichard D. LaneAnna AlkozeiJennifer BaoCourtney SmithAnna SanovaMatthew NettlesWilliam D. S. KillgoreNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ryan Smith Richard D. Lane Anna Alkozei Jennifer Bao Courtney Smith Anna Sanova Matthew Nettles William D. S. Killgore The role of medial prefrontal cortex in the working memory maintenance of one’s own emotional responses
description	Abstract The role of medial prefrontal cortex (MPFC) in maintaining emotional information within working memory (WM) remains insufficiently investigated – with some studies suggesting this process activates MPFC and others suggesting its activity is suppressed. To reconcile these different results, we asked 26 healthy participants to complete a WM task involving the maintenance of emotional content (EWM), visual content (VWM), or no content (“rest”) after exposure to emotion-provoking images. We also assessed individual differences in emotional awareness (EA). We observed that dorsal MPFC was more active during EWM than VWM; further, relative to the rest condition, both of these WM conditions involved suppression of ventral MPFC. We also observed that the dorsal anterior cingulate subregion of dorsal MPFC was positively associated with EA. We discuss how these results may be able to reconcile the findings of previous EWM studies, and extend understanding of the relationship between MPFC, EA, and WM.
format	article
author	Ryan Smith Richard D. Lane Anna Alkozei Jennifer Bao Courtney Smith Anna Sanova Matthew Nettles William D. S. Killgore
author_facet	Ryan Smith Richard D. Lane Anna Alkozei Jennifer Bao Courtney Smith Anna Sanova Matthew Nettles William D. S. Killgore
author_sort	Ryan Smith
title	The role of medial prefrontal cortex in the working memory maintenance of one’s own emotional responses
title_short	The role of medial prefrontal cortex in the working memory maintenance of one’s own emotional responses
title_full	The role of medial prefrontal cortex in the working memory maintenance of one’s own emotional responses
title_fullStr	The role of medial prefrontal cortex in the working memory maintenance of one’s own emotional responses
title_full_unstemmed	The role of medial prefrontal cortex in the working memory maintenance of one’s own emotional responses
title_sort	role of medial prefrontal cortex in the working memory maintenance of one’s own emotional responses
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/3ba6237a50f24a49b5589856868cfe01
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The role of medial prefrontal cortex in the working memory maintenance of one’s own emotional responses

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