Continuous 24-hour ocular dimensional profile recording in medically treated normal-tension glaucoma

Jacky WY Lee,1,2 Lin Fu,1 Jennifer WH Shum,1 Jonathan CH Chan,3 Jimmy SM Lai1 1Department of Ophthalmology, The University of Hong Kong, Hong Kong; 2Department of Ophthalmology, Caritas Medical Centre, Hong Kong; 3Department of Ophthalmology, Queen Mary Hospital, Hong Kong Purpose: To analyze the...

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Autores principales:	Lee JWY, Fu L, Shum JWH, Chan JCH, Lai JS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/3baa02dbae4b4d1fab48e882ff479457
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spelling	oai:doaj.org-article:3baa02dbae4b4d1fab48e882ff4794572021-12-02T02:54:00ZContinuous 24-hour ocular dimensional profile recording in medically treated normal-tension glaucoma1177-5483https://doaj.org/article/3baa02dbae4b4d1fab48e882ff4794572015-01-01T00:00:00Zhttp://www.dovepress.com/continuous-24-hour-ocular-dimensional-profile-recording-in-medically-t-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483 Jacky WY Lee,1,2 Lin Fu,1 Jennifer WH Shum,1 Jonathan CH Chan,3 Jimmy SM Lai1 1Department of Ophthalmology, The University of Hong Kong, Hong Kong; 2Department of Ophthalmology, Caritas Medical Centre, Hong Kong; 3Department of Ophthalmology, Queen Mary Hospital, Hong Kong Purpose: To analyze the 24-hour ocular dimensional profile in normal-tension glaucoma (NTG) patients on medical treatment.Methods: Consecutive, medically treated NTG subjects were recruited from a university eye center. Subjects were on a mean of 1.7±0.7 types of antiglaucoma medications and 56.6% were on a prostaglandin analog. A contact lens-based sensor device was worn in one eye of NTG patients to record the intraocular pressure (IOP)-related profile for 24 hours, recording the following: variability from mean over 24 hours, nocturnally and diurnally, as well as the number of peaks and troughs diurnally and nocturnally.Results: In 18 NTG subjects, the nocturnal variability around the mean contact lens-based sensor device signal was 48.9% less than the diurnal variability around the mean. The number of peaks was 54.7% less during the nocturnal period than during the diurnal period. The rate of increase in the ocular dimensional profile when going to sleep was significantly greater than the rate of decrease upon waking (P<0.001).Conclusion: In medically treated NTG subjects, there was more variability in the IOP-related pattern during the daytime and there were fewer peaks during sleep. Keywords: intraocular pressure, 24-hour, normal tension glaucomaLee JWYFu LShum JWHChan JCHLai JSDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 197-202 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Lee JWY Fu L Shum JWH Chan JCH Lai JS Continuous 24-hour ocular dimensional profile recording in medically treated normal-tension glaucoma
description	Jacky WY Lee,1,2 Lin Fu,1 Jennifer WH Shum,1 Jonathan CH Chan,3 Jimmy SM Lai1 1Department of Ophthalmology, The University of Hong Kong, Hong Kong; 2Department of Ophthalmology, Caritas Medical Centre, Hong Kong; 3Department of Ophthalmology, Queen Mary Hospital, Hong Kong Purpose: To analyze the 24-hour ocular dimensional profile in normal-tension glaucoma (NTG) patients on medical treatment.Methods: Consecutive, medically treated NTG subjects were recruited from a university eye center. Subjects were on a mean of 1.7±0.7 types of antiglaucoma medications and 56.6% were on a prostaglandin analog. A contact lens-based sensor device was worn in one eye of NTG patients to record the intraocular pressure (IOP)-related profile for 24 hours, recording the following: variability from mean over 24 hours, nocturnally and diurnally, as well as the number of peaks and troughs diurnally and nocturnally.Results: In 18 NTG subjects, the nocturnal variability around the mean contact lens-based sensor device signal was 48.9% less than the diurnal variability around the mean. The number of peaks was 54.7% less during the nocturnal period than during the diurnal period. The rate of increase in the ocular dimensional profile when going to sleep was significantly greater than the rate of decrease upon waking (P<0.001).Conclusion: In medically treated NTG subjects, there was more variability in the IOP-related pattern during the daytime and there were fewer peaks during sleep. Keywords: intraocular pressure, 24-hour, normal tension glaucoma
format	article
author	Lee JWY Fu L Shum JWH Chan JCH Lai JS
author_facet	Lee JWY Fu L Shum JWH Chan JCH Lai JS
author_sort	Lee JWY
title	Continuous 24-hour ocular dimensional profile recording in medically treated normal-tension glaucoma
title_short	Continuous 24-hour ocular dimensional profile recording in medically treated normal-tension glaucoma
title_full	Continuous 24-hour ocular dimensional profile recording in medically treated normal-tension glaucoma
title_fullStr	Continuous 24-hour ocular dimensional profile recording in medically treated normal-tension glaucoma
title_full_unstemmed	Continuous 24-hour ocular dimensional profile recording in medically treated normal-tension glaucoma
title_sort	continuous 24-hour ocular dimensional profile recording in medically treated normal-tension glaucoma
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/3baa02dbae4b4d1fab48e882ff479457
work_keys_str_mv	AT leejwy continuous24houroculardimensionalprofilerecordinginmedicallytreatednormaltensionglaucoma AT ful continuous24houroculardimensionalprofilerecordinginmedicallytreatednormaltensionglaucoma AT shumjwh continuous24houroculardimensionalprofilerecordinginmedicallytreatednormaltensionglaucoma AT chanjch continuous24houroculardimensionalprofilerecordinginmedicallytreatednormaltensionglaucoma AT laijs continuous24houroculardimensionalprofilerecordinginmedicallytreatednormaltensionglaucoma
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Continuous 24-hour ocular dimensional profile recording in medically treated normal-tension glaucoma

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