Excisional Goniotomy in Latino Patients with Open-Angle Glaucoma: Outcomes Through 24 Months

Matthew Porter,1,2 Arnulfo Garza,3 Mark Gallardo1 1Private Practice, El Paso Eye Surgeons, P.A., El Paso, Texas, USA; 2Texas Tech University Health Sciences Center School of Medicine-Lubbock, Lubbock, TX, USA; 3Texas Tech University Paul L. Foster School of Medicine, Lubbock, TX, USACorrespondence:...

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Autores principales:	Porter M, Garza A, Gallardo M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	glaucoma intraocular pressure excisional goniotomy kahook dual blade latino Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/3bac919a07a64c20a35fe84894ef830f
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spelling	oai:doaj.org-article:3bac919a07a64c20a35fe84894ef830f2021-12-02T12:15:26ZExcisional Goniotomy in Latino Patients with Open-Angle Glaucoma: Outcomes Through 24 Months1177-5483https://doaj.org/article/3bac919a07a64c20a35fe84894ef830f2020-10-01T00:00:00Zhttps://www.dovepress.com/excisional-goniotomy-in-latino-patients-with-open-angle-glaucoma-outco-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Matthew Porter,1,2 Arnulfo Garza,3 Mark Gallardo1 1Private Practice, El Paso Eye Surgeons, P.A., El Paso, Texas, USA; 2Texas Tech University Health Sciences Center School of Medicine-Lubbock, Lubbock, TX, USA; 3Texas Tech University Paul L. Foster School of Medicine, Lubbock, TX, USACorrespondence: Mark Gallardo Private Practice, El Paso Eye Surgeons, P.A., 1201 N. Mesa, Ste G, El Paso, TX 79902, USAEmail gallardomark@hotmail.comPurpose: To characterize the efficacy of combined phacoemulsification and excisional goniotomy with the Kahook Dual Blade (KDB-phaco) in eyes of Latino adults with cataract and open-angle glaucoma (OAG).Methods: Health records of consecutive Latino patients undergoing KDB-phaco were retrospectively reviewed. Intraocular pressure (IOP) and IOP-lowering medication use were recorded at baseline and each postoperative visit through up to 24 months. Primary outcomes were reductions in IOP and medication use from baseline; secondary outcomes were the proportions of eyes achieving IOP reductions of ≥ 20% and medication reductions ≥ 1 medication from baseline. Subgroup analysis was conducted in eyes with high and low baseline IOP.Results: Data from 44 eyes of 32 Latino patients with OAG were analyzed. Mean IOP was 17.8 (0.7) mmHg at baseline and postoperatively ranged from 12.4 to 13.8 mmHg (p≥ 0.0003), representing mean IOP reductions of 4.2– 4.6 mmHg (19.7– 23.1%). Mean medication was 1.5 (0.2) medications per eye at baseline and postoperatively ranged from 0.2 to 1.0 (p≥ 0.0061), representing mean medication reductions of 0.7– 1.2 medications per eye (47.1– 87.2%). In the low baseline IOP group (< 18 mmHg), mean IOP was significantly reduced through Month 24 and medications through Month 12; in the high baseline IOP group (≥ 18 mmHg), IOP and medications were significantly reduced through Month 24. From Months 1– 24, IOP reductions of ≥ 20% were achieved by 48.4– 56.2% of eyes in the full cohort, by 20.0– 33.3% in the low IOP group, and by 66.7– 100% in the high IOP group; medication reductions of ≥ 1 medication were achieved by 72.0– 95.6%, 64.7– 94.2%, and 87.5– 100% of eyes, respectively.Conclusion: Combined KDB-phaco in eyes of Latino patients with glaucoma and cataract significantly lowers IOP and the need for IOP-lowering medications for up to 24 months and should be considered for such patients who warrant IOP reduction, medication reduction, or both.Keywords: glaucoma, intraocular pressure, excisional goniotomy, Kahook Dual Blade, LatinoPorter MGarza AGallardo MDove Medical Pressarticleglaucomaintraocular pressureexcisional goniotomykahook dual bladelatinoOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 3619-3625 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	glaucoma intraocular pressure excisional goniotomy kahook dual blade latino Ophthalmology RE1-994
spellingShingle	glaucoma intraocular pressure excisional goniotomy kahook dual blade latino Ophthalmology RE1-994 Porter M Garza A Gallardo M Excisional Goniotomy in Latino Patients with Open-Angle Glaucoma: Outcomes Through 24 Months
description	Matthew Porter,1,2 Arnulfo Garza,3 Mark Gallardo1 1Private Practice, El Paso Eye Surgeons, P.A., El Paso, Texas, USA; 2Texas Tech University Health Sciences Center School of Medicine-Lubbock, Lubbock, TX, USA; 3Texas Tech University Paul L. Foster School of Medicine, Lubbock, TX, USACorrespondence: Mark Gallardo Private Practice, El Paso Eye Surgeons, P.A., 1201 N. Mesa, Ste G, El Paso, TX 79902, USAEmail gallardomark@hotmail.comPurpose: To characterize the efficacy of combined phacoemulsification and excisional goniotomy with the Kahook Dual Blade (KDB-phaco) in eyes of Latino adults with cataract and open-angle glaucoma (OAG).Methods: Health records of consecutive Latino patients undergoing KDB-phaco were retrospectively reviewed. Intraocular pressure (IOP) and IOP-lowering medication use were recorded at baseline and each postoperative visit through up to 24 months. Primary outcomes were reductions in IOP and medication use from baseline; secondary outcomes were the proportions of eyes achieving IOP reductions of ≥ 20% and medication reductions ≥ 1 medication from baseline. Subgroup analysis was conducted in eyes with high and low baseline IOP.Results: Data from 44 eyes of 32 Latino patients with OAG were analyzed. Mean IOP was 17.8 (0.7) mmHg at baseline and postoperatively ranged from 12.4 to 13.8 mmHg (p≥ 0.0003), representing mean IOP reductions of 4.2– 4.6 mmHg (19.7– 23.1%). Mean medication was 1.5 (0.2) medications per eye at baseline and postoperatively ranged from 0.2 to 1.0 (p≥ 0.0061), representing mean medication reductions of 0.7– 1.2 medications per eye (47.1– 87.2%). In the low baseline IOP group (< 18 mmHg), mean IOP was significantly reduced through Month 24 and medications through Month 12; in the high baseline IOP group (≥ 18 mmHg), IOP and medications were significantly reduced through Month 24. From Months 1– 24, IOP reductions of ≥ 20% were achieved by 48.4– 56.2% of eyes in the full cohort, by 20.0– 33.3% in the low IOP group, and by 66.7– 100% in the high IOP group; medication reductions of ≥ 1 medication were achieved by 72.0– 95.6%, 64.7– 94.2%, and 87.5– 100% of eyes, respectively.Conclusion: Combined KDB-phaco in eyes of Latino patients with glaucoma and cataract significantly lowers IOP and the need for IOP-lowering medications for up to 24 months and should be considered for such patients who warrant IOP reduction, medication reduction, or both.Keywords: glaucoma, intraocular pressure, excisional goniotomy, Kahook Dual Blade, Latino
format	article
author	Porter M Garza A Gallardo M
author_facet	Porter M Garza A Gallardo M
author_sort	Porter M
title	Excisional Goniotomy in Latino Patients with Open-Angle Glaucoma: Outcomes Through 24 Months
title_short	Excisional Goniotomy in Latino Patients with Open-Angle Glaucoma: Outcomes Through 24 Months
title_full	Excisional Goniotomy in Latino Patients with Open-Angle Glaucoma: Outcomes Through 24 Months
title_fullStr	Excisional Goniotomy in Latino Patients with Open-Angle Glaucoma: Outcomes Through 24 Months
title_full_unstemmed	Excisional Goniotomy in Latino Patients with Open-Angle Glaucoma: Outcomes Through 24 Months
title_sort	excisional goniotomy in latino patients with open-angle glaucoma: outcomes through 24 months
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/3bac919a07a64c20a35fe84894ef830f
work_keys_str_mv	AT porterm excisionalgoniotomyinlatinopatientswithopenangleglaucomaoutcomesthrough24months AT garzaa excisionalgoniotomyinlatinopatientswithopenangleglaucomaoutcomesthrough24months AT gallardom excisionalgoniotomyinlatinopatientswithopenangleglaucomaoutcomesthrough24months
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Excisional Goniotomy in Latino Patients with Open-Angle Glaucoma: Outcomes Through 24 Months

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