Dendritic cells from Crohn's disease patients show aberrant STAT1 and STAT3 signaling.

Abnormalities of dendritic cells (DCs) and STAT proteins have been reported in Crohn's disease (CD). Studies on JAK/STAT signaling in DCs are, however, lacking in CD. We applied a flowcytometric single-cell-based phosphoepitope assay to evaluate STAT1 and STAT3 pathways in DC subsets from CD pa...

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Autores principales: Janne K Nieminen, Mirja Niemi, Taina Sipponen, Harri M Salo, Paula Klemetti, Martti Färkkilä, Jukka Vakkila, Outi Vaarala
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/3bafaa11e0354d1e91441107affa76d9
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