Lateral inhibition by Martinotti interneurons is facilitated by cholinergic inputs in human and mouse neocortex

Parvalbumin and somatostatin expressing interneurons mediate lateral inhibition between cortical neurons. Here the authors report the mechanisms by which acetylcholine from the basal forebrain selectively augments lateral inhibition via Martinotti cells and show that this is conserved in humans.

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Bibliographic Details
Main Authors: Joshua Obermayer, Tim S. Heistek, Amber Kerkhofs, Natalia A. Goriounova, Tim Kroon, Johannes C. Baayen, Sander Idema, Guilherme Testa-Silva, Jonathan J. Couey, Huibert D. Mansvelder
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/3bb32f558e4e41c8984accb0680d2e97
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