A computational approach for identifying the chemical factors involved in the glycosaminoglycans-mediated acceleration of amyloid fibril formation.
<h4>Background</h4>Amyloid fibril formation is the hallmark of many human diseases, including Alzheimer's disease, type II diabetes and amyloidosis. Amyloid fibrils deposit in the extracellular space and generally co-localize with the glycosaminoglycans (GAGs) of the basement membra...
Guardado en:
Autores principales: | Elodie Monsellier, Matteo Ramazzotti, Niccolò Taddei, Fabrizio Chiti |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/3bb64fc85d6b4834a1577cb347d59b35 |
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