Quantitative three-dimensional image analysis of the superior canal after surgical plugging to treat superior semicircular canal dehiscence

Abstract Surgical plugging to treat superior semicircular canal dehiscence (SCD) has been proven to impede the effect of the third mobile window, abating cochleovestibular symptoms. Knowledge of superior semicircular canal (SC)-plugging status has been proposed to serve as a guide for adjuvant treat...

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Autores principales:	Sang-Yeon Lee, Yein Lee, Jun Young Choi, Yun Jung Bae, MinJu Kim, Jae-Jin Song, Byung Yoon Choi, Won-Ki Jeong, Ja-Won Koo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/3bc5a4300782404db3986306a2e9f0b4
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spelling	oai:doaj.org-article:3bc5a4300782404db3986306a2e9f0b42021-12-02T18:50:57ZQuantitative three-dimensional image analysis of the superior canal after surgical plugging to treat superior semicircular canal dehiscence10.1038/s41598-021-95063-x2045-2322https://doaj.org/article/3bc5a4300782404db3986306a2e9f0b42021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-95063-xhttps://doaj.org/toc/2045-2322Abstract Surgical plugging to treat superior semicircular canal dehiscence (SCD) has been proven to impede the effect of the third mobile window, abating cochleovestibular symptoms. Knowledge of superior semicircular canal (SC)-plugging status has been proposed to serve as a guide for adjuvant treatment. Here, we investigated disturbances in the inner ear fluid space following SC plugging using a novel three-dimensional (3D) reconstruction-based method. This approach used a semi-automatic segmentation algorithm and a direct volume rendering method derived from conventional magnetic resonance images. The variable extents of filling defects at the sites of SC plugging and the positional relation of the defect to the ampulla and common crus were identified. The success group exhibited markedly reduced volumes following surgery, whereas the failure group displayed no changes in volume. These results indicate that the success or failure of SC plugging was related to 3D volume changes in the labyrinth fluid signal. Collectively, this study presents individualized SC-plugging statuses using a novel 3D reconstruction-based method and it facilitates future work regarding easy-to-measure 3D volume changes. This current technology also aids in the exploration of pathologic changes in various targets of interest.Sang-Yeon LeeYein LeeJun Young ChoiYun Jung BaeMinJu KimJae-Jin SongByung Yoon ChoiWon-Ki JeongJa-Won KooNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Sang-Yeon Lee Yein Lee Jun Young Choi Yun Jung Bae MinJu Kim Jae-Jin Song Byung Yoon Choi Won-Ki Jeong Ja-Won Koo Quantitative three-dimensional image analysis of the superior canal after surgical plugging to treat superior semicircular canal dehiscence
description	Abstract Surgical plugging to treat superior semicircular canal dehiscence (SCD) has been proven to impede the effect of the third mobile window, abating cochleovestibular symptoms. Knowledge of superior semicircular canal (SC)-plugging status has been proposed to serve as a guide for adjuvant treatment. Here, we investigated disturbances in the inner ear fluid space following SC plugging using a novel three-dimensional (3D) reconstruction-based method. This approach used a semi-automatic segmentation algorithm and a direct volume rendering method derived from conventional magnetic resonance images. The variable extents of filling defects at the sites of SC plugging and the positional relation of the defect to the ampulla and common crus were identified. The success group exhibited markedly reduced volumes following surgery, whereas the failure group displayed no changes in volume. These results indicate that the success or failure of SC plugging was related to 3D volume changes in the labyrinth fluid signal. Collectively, this study presents individualized SC-plugging statuses using a novel 3D reconstruction-based method and it facilitates future work regarding easy-to-measure 3D volume changes. This current technology also aids in the exploration of pathologic changes in various targets of interest.
format	article
author	Sang-Yeon Lee Yein Lee Jun Young Choi Yun Jung Bae MinJu Kim Jae-Jin Song Byung Yoon Choi Won-Ki Jeong Ja-Won Koo
author_facet	Sang-Yeon Lee Yein Lee Jun Young Choi Yun Jung Bae MinJu Kim Jae-Jin Song Byung Yoon Choi Won-Ki Jeong Ja-Won Koo
author_sort	Sang-Yeon Lee
title	Quantitative three-dimensional image analysis of the superior canal after surgical plugging to treat superior semicircular canal dehiscence
title_short	Quantitative three-dimensional image analysis of the superior canal after surgical plugging to treat superior semicircular canal dehiscence
title_full	Quantitative three-dimensional image analysis of the superior canal after surgical plugging to treat superior semicircular canal dehiscence
title_fullStr	Quantitative three-dimensional image analysis of the superior canal after surgical plugging to treat superior semicircular canal dehiscence
title_full_unstemmed	Quantitative three-dimensional image analysis of the superior canal after surgical plugging to treat superior semicircular canal dehiscence
title_sort	quantitative three-dimensional image analysis of the superior canal after surgical plugging to treat superior semicircular canal dehiscence
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/3bc5a4300782404db3986306a2e9f0b4
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Quantitative three-dimensional image analysis of the superior canal after surgical plugging to treat superior semicircular canal dehiscence

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