Microporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering

Microporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering

Injectable hydrogels could be used to repair bone defects. Here the authors incorporate nanoclay particles into chitosan creating an interconnected microporous hydrogel and show that this hydrogel can support MSC proliferation and differentiation in vitro, and support the recruitment of native cells...

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Autores principales: Zhong-Kai Cui, Soyon Kim, Jessalyn J. Baljon, Benjamin M. Wu, Tara Aghaloo, Min Lee
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/3bc7df5ac80b4ff0aec78ef14a5c5d9f
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spelling oai:doaj.org-article:3bc7df5ac80b4ff0aec78ef14a5c5d9f2021-12-02T14:38:42ZMicroporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering10.1038/s41467-019-11511-32041-1723https://doaj.org/article/3bc7df5ac80b4ff0aec78ef14a5c5d9f2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11511-3https://doaj.org/toc/2041-1723Injectable hydrogels could be used to repair bone defects. Here the authors incorporate nanoclay particles into chitosan creating an interconnected microporous hydrogel and show that this hydrogel can support MSC proliferation and differentiation in vitro, and support the recruitment of native cells and bone regeneration in a mouse calvarial defect model.Zhong-Kai CuiSoyon KimJessalyn J. BaljonBenjamin M. WuTara AghalooMin LeeNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zhong-Kai Cui
Soyon Kim
Jessalyn J. Baljon
Benjamin M. Wu
Tara Aghaloo
Min Lee
Microporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering
description Injectable hydrogels could be used to repair bone defects. Here the authors incorporate nanoclay particles into chitosan creating an interconnected microporous hydrogel and show that this hydrogel can support MSC proliferation and differentiation in vitro, and support the recruitment of native cells and bone regeneration in a mouse calvarial defect model.
format article
author Zhong-Kai Cui
Soyon Kim
Jessalyn J. Baljon
Benjamin M. Wu
Tara Aghaloo
Min Lee
author_facet Zhong-Kai Cui
Soyon Kim
Jessalyn J. Baljon
Benjamin M. Wu
Tara Aghaloo
Min Lee
author_sort Zhong-Kai Cui
title Microporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering
title_short Microporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering
title_full Microporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering
title_fullStr Microporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering
title_full_unstemmed Microporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering
title_sort microporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/3bc7df5ac80b4ff0aec78ef14a5c5d9f
work_keys_str_mv AT zhongkaicui microporousmethacrylatedglycolchitosanmontmorillonitenanocompositehydrogelforbonetissueengineering
AT soyonkim microporousmethacrylatedglycolchitosanmontmorillonitenanocompositehydrogelforbonetissueengineering
AT jessalynjbaljon microporousmethacrylatedglycolchitosanmontmorillonitenanocompositehydrogelforbonetissueengineering
AT benjaminmwu microporousmethacrylatedglycolchitosanmontmorillonitenanocompositehydrogelforbonetissueengineering
AT taraaghaloo microporousmethacrylatedglycolchitosanmontmorillonitenanocompositehydrogelforbonetissueengineering
AT minlee microporousmethacrylatedglycolchitosanmontmorillonitenanocompositehydrogelforbonetissueengineering
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