Gallbladder Cancer: Current Insights in Genetic Alterations and Their Possible Therapeutic Implications

Gallbladder Cancer: Current Insights in Genetic Alterations and Their Possible Therapeutic Implications

Due to the fast progression in molecular technologies such as next-generation sequencing, knowledge of genetic alterations in gallbladder cancer (GBC) increases. This systematic review provides an overview of frequently occurring genetic alterations occurring in GBC and their possible therapeutic im...

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Autores principales: Hendrien Kuipers, Tessa J. J. de Bitter, Marieke T. de Boer, Rachel S. van der Post, Maarten W. Nijkamp, Philip R. de Reuver, Rudolf S. N. Fehrmann, Frederik J. H. Hoogwater
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
gallbladder cancer
gene mutations
genetic alterations
tumor mutational burden
microsatellite instability
targeted therapy
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/3bcaf37b434c4c129dc68b05009fc95b
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https://doaj.org/article/3bcaf37b434c4c129dc68b05009fc95b

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