Beyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis

Resistance proteins are perceived as mechanisms protecting bacteria from the inhibitory effect of their produced antibiotics or antibiotics from competitors. Here, we report that antibiotic resistance proteins regulate lincomycin biosynthesis in response to subinhibitory concentrations of antibioti...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Marketa Koberska, Ludmila Vesela, Vladimir Vimberg, Jakub Lenart, Jana Vesela, Zdenek Kamenik, Jiri Janata, Gabriela Balikova Novotna
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/3bd1fc7128384750a9b8a74a263ebdfe
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:3bd1fc7128384750a9b8a74a263ebdfe
record_format	dspace
spelling	oai:doaj.org-article:3bd1fc7128384750a9b8a74a263ebdfe2021-11-03T21:52:35ZBeyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis2150-751110.1128/mBio.01731-21https://doaj.org/article/3bd1fc7128384750a9b8a74a263ebdfe2021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01731-21https://doaj.org/toc/2150-7511 Resistance proteins are perceived as mechanisms protecting bacteria from the inhibitory effect of their produced antibiotics or antibiotics from competitors. Here, we report that antibiotic resistance proteins regulate lincomycin biosynthesis in response to subinhibitory concentrations of antibiotics.Marketa KoberskaLudmila VeselaVladimir VimbergJakub LenartJana VeselaZdenek KamenikJiri JanataGabriela Balikova NovotnaAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Marketa Koberska Ludmila Vesela Vladimir Vimberg Jakub Lenart Jana Vesela Zdenek Kamenik Jiri Janata Gabriela Balikova Novotna Beyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis
description	Resistance proteins are perceived as mechanisms protecting bacteria from the inhibitory effect of their produced antibiotics or antibiotics from competitors. Here, we report that antibiotic resistance proteins regulate lincomycin biosynthesis in response to subinhibitory concentrations of antibiotics.
format	article
author	Marketa Koberska Ludmila Vesela Vladimir Vimberg Jakub Lenart Jana Vesela Zdenek Kamenik Jiri Janata Gabriela Balikova Novotna
author_facet	Marketa Koberska Ludmila Vesela Vladimir Vimberg Jakub Lenart Jana Vesela Zdenek Kamenik Jiri Janata Gabriela Balikova Novotna
author_sort	Marketa Koberska
title	Beyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis
title_short	Beyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis
title_full	Beyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis
title_fullStr	Beyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis
title_full_unstemmed	Beyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis
title_sort	beyond self-resistance: abcf atpase lmrc is a signal-transducing component of an antibiotic-driven signaling cascade accelerating the onset of lincomycin biosynthesis
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/3bd1fc7128384750a9b8a74a263ebdfe
work_keys_str_mv	AT marketakoberska beyondselfresistanceabcfatpaselmrcisasignaltransducingcomponentofanantibioticdrivensignalingcascadeacceleratingtheonsetoflincomycinbiosynthesis AT ludmilavesela beyondselfresistanceabcfatpaselmrcisasignaltransducingcomponentofanantibioticdrivensignalingcascadeacceleratingtheonsetoflincomycinbiosynthesis AT vladimirvimberg beyondselfresistanceabcfatpaselmrcisasignaltransducingcomponentofanantibioticdrivensignalingcascadeacceleratingtheonsetoflincomycinbiosynthesis AT jakublenart beyondselfresistanceabcfatpaselmrcisasignaltransducingcomponentofanantibioticdrivensignalingcascadeacceleratingtheonsetoflincomycinbiosynthesis AT janavesela beyondselfresistanceabcfatpaselmrcisasignaltransducingcomponentofanantibioticdrivensignalingcascadeacceleratingtheonsetoflincomycinbiosynthesis AT zdenekkamenik beyondselfresistanceabcfatpaselmrcisasignaltransducingcomponentofanantibioticdrivensignalingcascadeacceleratingtheonsetoflincomycinbiosynthesis AT jirijanata beyondselfresistanceabcfatpaselmrcisasignaltransducingcomponentofanantibioticdrivensignalingcascadeacceleratingtheonsetoflincomycinbiosynthesis AT gabrielabalikovanovotna beyondselfresistanceabcfatpaselmrcisasignaltransducingcomponentofanantibioticdrivensignalingcascadeacceleratingtheonsetoflincomycinbiosynthesis
_version_	1718445389561987072

Beyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis

Ejemplares similares