Molecular characterization of type I IFN-induced cytotoxicity in bladder cancer cells reveals biomarkers of resistance

Although anti-tumor activities of type I interferons (IFNs) have been recognized for decades, the molecular mechanisms contributing to clinical response remain poorly understood. The complex functions of these pleiotropic cytokines include stimulation of innate and adaptive immune responses against...

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Autores principales: Jennifer L. Green, Robin E. Osterhout, Amy L. Klova, Carsten Merkwirth, Scott R.P. McDonnell, Reza Beheshti Zavareh, Bryan C. Fuchs, Adeela Kamal, Jørn S. Jakobsen
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/3bdba8d9baec4171a65be46af11a81fb
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