Irritable bowel, chronic widespread pain, chronic fatigue and related syndromes are prevalent and highly overlapping in the general population: DanFunD

Abstract Prevalence of functional somatic syndromes (FSS) in the general population varies with observed overlap between syndromes. However, studies including a range of FSS are sparse. We investigated prevalence and characteristics of various FSS and the unifying diagnostic construct bodily distres...

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Autores principales: Marie Weinreich Petersen, Andreas Schröder, Torben Jørgensen, Eva Ørnbøl, Thomas Meinertz Dantoft, Marie Eliasen, Michael Eriksen Benros, Per Fink
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Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/3bdbf45bc96b42338482cfb9e3fc804b
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spelling oai:doaj.org-article:3bdbf45bc96b42338482cfb9e3fc804b2021-12-02T10:59:18ZIrritable bowel, chronic widespread pain, chronic fatigue and related syndromes are prevalent and highly overlapping in the general population: DanFunD10.1038/s41598-020-60318-62045-2322https://doaj.org/article/3bdbf45bc96b42338482cfb9e3fc804b2020-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-60318-6https://doaj.org/toc/2045-2322Abstract Prevalence of functional somatic syndromes (FSS) in the general population varies with observed overlap between syndromes. However, studies including a range of FSS are sparse. We investigated prevalence and characteristics of various FSS and the unifying diagnostic construct bodily distress syndrome (BDS), and identified mutual overlap of the FSS and their overlap with BDS. We included a stratified subsample of 1590 adults from a randomly selected Danish general population sample (n = 7493). Telephonic diagnostic interviews performed by three trained physicians were used to identify individuals with FSS and BDS. Prevalence of overall FSS was 9.3%; 3.8% for irritable bowel, 2.2% for chronic widespread pain, 6.1% for chronic fatigue, 1.5% for whiplash associated disorders, and 0.9% for multiple chemical sensitivity. Prevalence of BDS was 10.7% where 2.0% had the multi-organ type. FSS were highly overlapping with low likelihood of having a “pure” type. Diagnostic agreement of FSS and BDS was 92.0%. Multi-syndromatic FSS and multi-organ BDS were associated with female sex, poor health, physical limitations, and comorbidity. FSS are highly prevalent and overlapping, and multi-syndromatic cases are most affected. BDS captured the majority of FSS and may improve clinical management, making the distinction between multi- and mono-syndromatic patients easier.Marie Weinreich PetersenAndreas SchröderTorben JørgensenEva ØrnbølThomas Meinertz DantoftMarie EliasenMichael Eriksen BenrosPer FinkNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Marie Weinreich Petersen
Andreas Schröder
Torben Jørgensen
Eva Ørnbøl
Thomas Meinertz Dantoft
Marie Eliasen
Michael Eriksen Benros
Per Fink
Irritable bowel, chronic widespread pain, chronic fatigue and related syndromes are prevalent and highly overlapping in the general population: DanFunD
description Abstract Prevalence of functional somatic syndromes (FSS) in the general population varies with observed overlap between syndromes. However, studies including a range of FSS are sparse. We investigated prevalence and characteristics of various FSS and the unifying diagnostic construct bodily distress syndrome (BDS), and identified mutual overlap of the FSS and their overlap with BDS. We included a stratified subsample of 1590 adults from a randomly selected Danish general population sample (n = 7493). Telephonic diagnostic interviews performed by three trained physicians were used to identify individuals with FSS and BDS. Prevalence of overall FSS was 9.3%; 3.8% for irritable bowel, 2.2% for chronic widespread pain, 6.1% for chronic fatigue, 1.5% for whiplash associated disorders, and 0.9% for multiple chemical sensitivity. Prevalence of BDS was 10.7% where 2.0% had the multi-organ type. FSS were highly overlapping with low likelihood of having a “pure” type. Diagnostic agreement of FSS and BDS was 92.0%. Multi-syndromatic FSS and multi-organ BDS were associated with female sex, poor health, physical limitations, and comorbidity. FSS are highly prevalent and overlapping, and multi-syndromatic cases are most affected. BDS captured the majority of FSS and may improve clinical management, making the distinction between multi- and mono-syndromatic patients easier.
format article
author Marie Weinreich Petersen
Andreas Schröder
Torben Jørgensen
Eva Ørnbøl
Thomas Meinertz Dantoft
Marie Eliasen
Michael Eriksen Benros
Per Fink
author_facet Marie Weinreich Petersen
Andreas Schröder
Torben Jørgensen
Eva Ørnbøl
Thomas Meinertz Dantoft
Marie Eliasen
Michael Eriksen Benros
Per Fink
author_sort Marie Weinreich Petersen
title Irritable bowel, chronic widespread pain, chronic fatigue and related syndromes are prevalent and highly overlapping in the general population: DanFunD
title_short Irritable bowel, chronic widespread pain, chronic fatigue and related syndromes are prevalent and highly overlapping in the general population: DanFunD
title_full Irritable bowel, chronic widespread pain, chronic fatigue and related syndromes are prevalent and highly overlapping in the general population: DanFunD
title_fullStr Irritable bowel, chronic widespread pain, chronic fatigue and related syndromes are prevalent and highly overlapping in the general population: DanFunD
title_full_unstemmed Irritable bowel, chronic widespread pain, chronic fatigue and related syndromes are prevalent and highly overlapping in the general population: DanFunD
title_sort irritable bowel, chronic widespread pain, chronic fatigue and related syndromes are prevalent and highly overlapping in the general population: danfund
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/3bdbf45bc96b42338482cfb9e3fc804b
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