LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc

LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc

lncRNA and cellular metabolism are frequently dysregulated in cancer. In this study, the authors discover the lncGLCC1 is increased in colorectal cancer cells under glucose starvation conditions and correlates with poor prognosis in this cancer.

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Detalles Bibliográficos
Autores principales: Jiayin Tang, Tingting Yan, Yujie Bao, Chaoqin Shen, Chenyang Yu, Xiaoqiang Zhu, Xianglong Tian, Fangfang Guo, Qian Liang, Qiang Liu, Ming Zhong, Jinxian Chen, Zhizheng Ge, Xiaobo Li, Xiaoyu Chen, Yun Cui, Yingxuan Chen, Weiping Zou, Haoyan Chen, Jie Hong, Jing-Yuan Fang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
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Acceso en línea:https://doaj.org/article/3bdfa59d5ab74709ab6814e3fa0fb544
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Descripción
Sumario:lncRNA and cellular metabolism are frequently dysregulated in cancer. In this study, the authors discover the lncGLCC1 is increased in colorectal cancer cells under glucose starvation conditions and correlates with poor prognosis in this cancer.

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