LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc

lncRNA and cellular metabolism are frequently dysregulated in cancer. In this study, the authors discover the lncGLCC1 is increased in colorectal cancer cells under glucose starvation conditions and correlates with poor prognosis in this cancer.

Guardado en:

Detalles Bibliográficos
Autores principales:	Jiayin Tang, Tingting Yan, Yujie Bao, Chaoqin Shen, Chenyang Yu, Xiaoqiang Zhu, Xianglong Tian, Fangfang Guo, Qian Liang, Qiang Liu, Ming Zhong, Jinxian Chen, Zhizheng Ge, Xiaobo Li, Xiaoyu Chen, Yun Cui, Yingxuan Chen, Weiping Zou, Haoyan Chen, Jie Hong, Jing-Yuan Fang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/3bdfa59d5ab74709ab6814e3fa0fb544
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:3bdfa59d5ab74709ab6814e3fa0fb544
record_format	dspace
spelling	oai:doaj.org-article:3bdfa59d5ab74709ab6814e3fa0fb5442021-12-02T16:57:11ZLncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc10.1038/s41467-019-11447-82041-1723https://doaj.org/article/3bdfa59d5ab74709ab6814e3fa0fb5442019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11447-8https://doaj.org/toc/2041-1723lncRNA and cellular metabolism are frequently dysregulated in cancer. In this study, the authors discover the lncGLCC1 is increased in colorectal cancer cells under glucose starvation conditions and correlates with poor prognosis in this cancer.Jiayin TangTingting YanYujie BaoChaoqin ShenChenyang YuXiaoqiang ZhuXianglong TianFangfang GuoQian LiangQiang LiuMing ZhongJinxian ChenZhizheng GeXiaobo LiXiaoyu ChenYun CuiYingxuan ChenWeiping ZouHaoyan ChenJie HongJing-Yuan FangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jiayin Tang Tingting Yan Yujie Bao Chaoqin Shen Chenyang Yu Xiaoqiang Zhu Xianglong Tian Fangfang Guo Qian Liang Qiang Liu Ming Zhong Jinxian Chen Zhizheng Ge Xiaobo Li Xiaoyu Chen Yun Cui Yingxuan Chen Weiping Zou Haoyan Chen Jie Hong Jing-Yuan Fang LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc
description	lncRNA and cellular metabolism are frequently dysregulated in cancer. In this study, the authors discover the lncGLCC1 is increased in colorectal cancer cells under glucose starvation conditions and correlates with poor prognosis in this cancer.
format	article
author	Jiayin Tang Tingting Yan Yujie Bao Chaoqin Shen Chenyang Yu Xiaoqiang Zhu Xianglong Tian Fangfang Guo Qian Liang Qiang Liu Ming Zhong Jinxian Chen Zhizheng Ge Xiaobo Li Xiaoyu Chen Yun Cui Yingxuan Chen Weiping Zou Haoyan Chen Jie Hong Jing-Yuan Fang
author_facet	Jiayin Tang Tingting Yan Yujie Bao Chaoqin Shen Chenyang Yu Xiaoqiang Zhu Xianglong Tian Fangfang Guo Qian Liang Qiang Liu Ming Zhong Jinxian Chen Zhizheng Ge Xiaobo Li Xiaoyu Chen Yun Cui Yingxuan Chen Weiping Zou Haoyan Chen Jie Hong Jing-Yuan Fang
author_sort	Jiayin Tang
title	LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc
title_short	LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc
title_full	LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc
title_fullStr	LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc
title_full_unstemmed	LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc
title_sort	lncrna glcc1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-myc
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/3bdfa59d5ab74709ab6814e3fa0fb544
work_keys_str_mv	AT jiayintang lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT tingtingyan lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT yujiebao lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT chaoqinshen lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT chenyangyu lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT xiaoqiangzhu lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT xianglongtian lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT fangfangguo lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT qianliang lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT qiangliu lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT mingzhong lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT jinxianchen lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT zhizhengge lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT xiaoboli lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT xiaoyuchen lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT yuncui lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT yingxuanchen lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT weipingzou lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT haoyanchen lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT jiehong lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc AT jingyuanfang lncrnaglcc1promotescolorectalcarcinogenesisandglucosemetabolismbystabilizingcmyc
_version_	1718382558879678464

LncRNA GLCC1 promotes colorectal carcinogenesis and glucose metabolism by stabilizing c-Myc

Ejemplares similares