Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection

The recalcitrance of many infections to antibiotic treatment may be due to the presence of ‘persisters’, or non-growing, antibiotic-tolerant bacteria. Here, the authors study the structures and functions of aminoacyl-tRNA acetyltransferase toxins, and their roles in persister formation in Salmonella...

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Autores principales: Julian A. Rycroft, Bridget Gollan, Grzegorz J. Grabe, Alexander Hall, Angela M. Cheverton, Gerald Larrouy-Maumus, Stephen A. Hare, Sophie Helaine
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/3bed1ef83f1d4e429b13f75bbb4a9545
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spelling oai:doaj.org-article:3bed1ef83f1d4e429b13f75bbb4a95452021-12-02T13:23:48ZActivity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection10.1038/s41467-018-04472-62041-1723https://doaj.org/article/3bed1ef83f1d4e429b13f75bbb4a95452018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04472-6https://doaj.org/toc/2041-1723The recalcitrance of many infections to antibiotic treatment may be due to the presence of ‘persisters’, or non-growing, antibiotic-tolerant bacteria. Here, the authors study the structures and functions of aminoacyl-tRNA acetyltransferase toxins, and their roles in persister formation in Salmonella.Julian A. RycroftBridget GollanGrzegorz J. GrabeAlexander HallAngela M. ChevertonGerald Larrouy-MaumusStephen A. HareSophie HelaineNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Julian A. Rycroft
Bridget Gollan
Grzegorz J. Grabe
Alexander Hall
Angela M. Cheverton
Gerald Larrouy-Maumus
Stephen A. Hare
Sophie Helaine
Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection
description The recalcitrance of many infections to antibiotic treatment may be due to the presence of ‘persisters’, or non-growing, antibiotic-tolerant bacteria. Here, the authors study the structures and functions of aminoacyl-tRNA acetyltransferase toxins, and their roles in persister formation in Salmonella.
format article
author Julian A. Rycroft
Bridget Gollan
Grzegorz J. Grabe
Alexander Hall
Angela M. Cheverton
Gerald Larrouy-Maumus
Stephen A. Hare
Sophie Helaine
author_facet Julian A. Rycroft
Bridget Gollan
Grzegorz J. Grabe
Alexander Hall
Angela M. Cheverton
Gerald Larrouy-Maumus
Stephen A. Hare
Sophie Helaine
author_sort Julian A. Rycroft
title Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection
title_short Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection
title_full Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection
title_fullStr Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection
title_full_unstemmed Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection
title_sort activity of acetyltransferase toxins involved in salmonella persister formation during macrophage infection
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/3bed1ef83f1d4e429b13f75bbb4a9545
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