Pre-clinical markers for diagnosis of diabetic nephropathy in patients with type 1 diabetes mellitus

Due to progressive nature of diabetic nephropathy (DN) and limited effectiveness of therapeutic efforts at clinically overt stages, diagnosisof pre-clinical (and, therefore, potentially reversible) DN is especially important. To date, however, test for microalbuminuriaremains the only technique appl...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Nadezhda Olegovna Lebedeva, Olga Konstantinovna Vikulova
Format: article
Langue:EN
RU
Publié: Endocrinology Research Centre 2012
Sujets:
Accès en ligne:https://doaj.org/article/3bf3572192ad4c81895f8fdbde1a086e
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
Description
Résumé:Due to progressive nature of diabetic nephropathy (DN) and limited effectiveness of therapeutic efforts at clinically overt stages, diagnosisof pre-clinical (and, therefore, potentially reversible) DN is especially important. To date, however, test for microalbuminuriaremains the only technique applicable for early diagnostics of DN. Current review addresses search for potential markers of pre-clinical stage of DN in patients with type 1 diabetes mellitus and embracesdata from latest experimental and clinical studies in this area.