Epstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child

Roberto Gallego-Pinazo1,2, Miguel Harto1, Jose J Garcia-Medina2,3, Inmaculada Serra1, Enrique España1, Maria D Pinazo-Duran2,41Ophthalmology Department, University Hospital, La Fe, Valencia, Spain; 2Ophthalmology Research Unit “Santiago Grisolia”, Valencia,...

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Autores principales: Roberto Gallego-Pinazo, Miguel Harto, Jose J Garcia-Medina, Inmaculada Serra, Enrique España, Maria D Pinazo-Duran
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Publicado: Dove Medical Press 2008
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spelling oai:doaj.org-article:3bff0412c0da42f9888bd2685885f5012021-12-02T02:08:46ZEpstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child1177-54671177-5483https://doaj.org/article/3bff0412c0da42f9888bd2685885f5012008-06-01T00:00:00Zhttp://www.dovepress.com/epstein-barr-virus-and-acute-retinal-necrosis-in-a-5-year-old-immunoco-a1800https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Roberto Gallego-Pinazo1,2, Miguel Harto1, Jose J Garcia-Medina2,3, Inmaculada Serra1, Enrique España1, Maria D Pinazo-Duran2,41Ophthalmology Department, University Hospital, La Fe, Valencia, Spain; 2Ophthalmology Research Unit “Santiago Grisolia”, Valencia, Spain; 3Ophthalmology Department, Hospital La inmaculada, Huercal-Overa, Spain; 4Ophthalmology Department, Hospital Punta de Europa, Algeciras, SpainObjective: To describe a case of bilateral acute retinal necrosis syndrome (ARNS) in a 5-year-old boy.Method: A retrospective, interventional case is described in one child attending the pediatric ophthalmology section, complaining of sudden bilateral red eye and haze-impaired vision. A standardized ophthalmologic examination and specific serological probes supported the diagnosis of severe bilateral ARNS in an immunocompetent child.Results: The reduced visual acuity (<20/400), the ocular fundus signs (perivasculitis, thrombosis and retinal edema) and the positive immunoglobulin M anti-Epstein Barr virus serology, lead us to the ARNS definitive diagnosis. Antiviral therapy (Acyclovir; Zovirax®), ciclopentolate dilating eye drops, and antiplatelet treatment (acetil salicylic acid; Aspirin®) were administered until recovering the final visual acuity (20/40).Conclusions: The ARNS is an ocular disease with poor prognosis, which in turns may display better course when determining the etiopathogenic virus and selecting the appropriate and precocious therapy.Keywords: retinal necrosis, Epstein-Barr virus, antiviral serology, antiviral therapy Roberto Gallego-PinazoMiguel HartoJose J Garcia-MedinaInmaculada SerraEnrique EspañaMaria D Pinazo-DuranDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2008, Iss Issue 2, Pp 451-455 (2008)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Roberto Gallego-Pinazo
Miguel Harto
Jose J Garcia-Medina
Inmaculada Serra
Enrique España
Maria D Pinazo-Duran
Epstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child
description Roberto Gallego-Pinazo1,2, Miguel Harto1, Jose J Garcia-Medina2,3, Inmaculada Serra1, Enrique España1, Maria D Pinazo-Duran2,41Ophthalmology Department, University Hospital, La Fe, Valencia, Spain; 2Ophthalmology Research Unit “Santiago Grisolia”, Valencia, Spain; 3Ophthalmology Department, Hospital La inmaculada, Huercal-Overa, Spain; 4Ophthalmology Department, Hospital Punta de Europa, Algeciras, SpainObjective: To describe a case of bilateral acute retinal necrosis syndrome (ARNS) in a 5-year-old boy.Method: A retrospective, interventional case is described in one child attending the pediatric ophthalmology section, complaining of sudden bilateral red eye and haze-impaired vision. A standardized ophthalmologic examination and specific serological probes supported the diagnosis of severe bilateral ARNS in an immunocompetent child.Results: The reduced visual acuity (<20/400), the ocular fundus signs (perivasculitis, thrombosis and retinal edema) and the positive immunoglobulin M anti-Epstein Barr virus serology, lead us to the ARNS definitive diagnosis. Antiviral therapy (Acyclovir; Zovirax®), ciclopentolate dilating eye drops, and antiplatelet treatment (acetil salicylic acid; Aspirin®) were administered until recovering the final visual acuity (20/40).Conclusions: The ARNS is an ocular disease with poor prognosis, which in turns may display better course when determining the etiopathogenic virus and selecting the appropriate and precocious therapy.Keywords: retinal necrosis, Epstein-Barr virus, antiviral serology, antiviral therapy
format article
author Roberto Gallego-Pinazo
Miguel Harto
Jose J Garcia-Medina
Inmaculada Serra
Enrique España
Maria D Pinazo-Duran
author_facet Roberto Gallego-Pinazo
Miguel Harto
Jose J Garcia-Medina
Inmaculada Serra
Enrique España
Maria D Pinazo-Duran
author_sort Roberto Gallego-Pinazo
title Epstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child
title_short Epstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child
title_full Epstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child
title_fullStr Epstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child
title_full_unstemmed Epstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child
title_sort epstein-barr virus and acute retinal necrosis in a 5-year-old immunocompetent child
publisher Dove Medical Press
publishDate 2008
url https://doaj.org/article/3bff0412c0da42f9888bd2685885f501
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